research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
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30 / 31 results research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research Light Pollution and Oxidative Stress: Effects on Retina and Human Health
Excessive blue light harms eye cells and disrupts sleep patterns.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Near the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research Regeneration, Wound Healing, and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
research Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes
Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
research Abstracts
Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.
research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia
Oxidative stress affects hair loss in men with androgenetic alopecia.
research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes
Blood vessels and specific genes help turn cartilage into bone when bones heal.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Pantothenic Acid Promotes Dermal Papilla Cell Proliferation in Hair Follicles of American Minks via Inhibitor of DNA Binding 3/Notch Signaling Pathway
Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions
Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
research Perspectives of Alopecia Behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype
The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis
Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
research Aging of the Hair Follicle Pigmentation System
Hair grays due to oxidative stress and fewer functioning melanocytes.
research An Ovol2-Zeb1 Transcriptional Circuit Regulates Epithelial Directional Migration and Proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties
Wounded skin cells can revert to stem cells and help heal.
research PRC2 Preserves Intestinal Progenitors and Restricts Secretory Lineage Commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research Spatio-Temporal Regulation of Gene Expression Defines Subpopulations of Epidermal Stem Cells
Different types of skin stem cells can change and adapt, which is important for developing new treatments.
research The Developmental Basis of Fingerprint Pattern Formation and Variation
Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research A Review of the Impact of Calorie Restriction on Stem Cell Potency
Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.