research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
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600-630 / 1000+ results research Roux-En-Y Gastric Bypass in the Treatment of Non-Classic Congenital Adrenal Hyperplasia Due to 11-Hydroxylase Deficiency
Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.
research Decoding the Complexity of Delayed Wound Healing Following Enterococcus Faecalis Infection
Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.
research The Many Faces of Calcineurin Inhibitor Toxicity—What the FK?
Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
research In Vivo Function of VDR in Gene Expression: VDR Knock-Out Mice
Vitamin D receptor is crucial for bone health and mineral metabolism.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice
A special stem cell fluid can speed up wound healing and hair growth in mice.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Comparison of the Acute Ultraviolet Photoresponse in Congenic Albino Hairless C57BL/6J Mice Relative to Outbred SKH1 Hairless Mice
B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury
Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.
research Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff
Using a special shampoo and scalp tonic together can greatly reduce severe dandruff and its causes.
research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle
New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.
research Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth
Three-dimensional culture helps dermal papilla cells grow new human hair follicles.
research Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect
Minoxidil helps hair growth by activating the β-catenin pathway.
research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research Perifollicular Vascularization: Cocultures and Tricultures Approaches to Study the Cross-Talk Between Microvascular Endothelial Cells, Follicle Papilla Cells, and Keratinocytes
Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss
Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.
research AXR3 and SHY2 Interact to Regulate Root Hair Development
AXR3 and SHY2 genes control the growth and timing of root hair development in plants.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Vitamin D3 Analogs Stimulate Hair Growth in Nude Mice
Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
research Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor
LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
research Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
Substance from human umbilical cord blood cells promotes hair growth.
research Diverse Cellular Players Orchestrate Regeneration After Wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Anagen Hair Follicles Transplanted Into Mature Human Scars Remodel Fibrotic Tissue
Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.