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In this study, distinct metabolic profiles were identified in women with PCOS, suggesting potential biomarkers for diagnosis based on changes in lipid and androgen metabolism.

This study introduced an innovative nanozyme system called MCP@G, which was shown to improve diabetic wound healing in rats by alleviating mitochondrial oxidative stress, enhancing fibroblast migration, and promoting blood vessel and hair follicle regeneration, offering a promising approach for treating challenging diabetic wounds.

In this study, partially purified apple polyphenols were found to inhibit preadipocyte differentiation in mouse cells by reducing GPDH activity and triglyceride accumulation.

This review highlights the roles of key transcription factors and signaling pathways in regulating olfactory epithelium regeneration, discussing recent advances in single-cell and spatial transcriptomics as well as organoid models to enhance understanding of olfactory regeneration mechanisms.

This review discusses how dysregulated levels of eicosanoids, which are metabolites of phospholipids, may contribute to skin diseases like psoriasis and atopic dermatitis, suggesting the importance of targeted eicosanoid control in diagnosis and treatment.

This study suggests that UMPP activation is a key signaling pathway in differentiating primary and secondary hair follicles in cashmere goats.

This study suggests that activating the PPARs/SHH-mitochondrial axis may enhance diabetic wound healing by improving endothelial cell metabolism and angiogenesis, indicating potential for PPAR agonists in treating diabetic foot ulcers.

In this study, researchers found that unexplained liver damage in PCOS patients may involve iron metabolism and the miR-761-hepcidin/GPX4 axis, suggesting potential therapeutic targets.

ALDOA levels drop in hair cells during hair loss.

This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.

This review discusses the potential of metabolic engineering to enable sustainable industrial-scale production of L-aspartate and its derivatives, detailing current microbial production progress, limiting factors, and future prospects with emerging technologies in synthetic biology.

This review article discusses recent progress in the extraction and potential health benefits of oligosaccharides from brown seaweeds, especially focusing on their antimicrobial, anti-inflammatory, and prebiotic properties, and possible applications in managing metabolic syndrome.

This study identified several rare genetic variants related to insulin resistance in women with PCOS, highlighting the potential for monogenic conditions in patients with extreme or atypical phenotypes.

The conclusion suggests that treatments targeting root causes of chronic diseases may be developed by focusing on gene expression and lifestyle factors.

This study found that procyanidin oligomers from apples and barley may stimulate hair growth by promoting hair epithelial cell proliferation and protecting them from apoptosis via MEK activation in a murine model.

This guide provides an overview of the complex roles and mechanisms of various receptors and channels in pharmacology but does not report new experimental results.

This study found that a synthetic polyphenol, dimeric 1,2,4-benzenetriol (diBTO), can coat gray hair and gradually oxidize, creating a resistant brown layer similar to apple browning, which offers a practical hair dyeing solution that withstands washing and reduces the need for long dyeing sessions.

This study found that activating both PKM2 and Wnt/β-catenin signaling pathways significantly enhanced hair regrowth and hair follicle neogenesis in mice, suggesting a potential strategy for treating alopecia.

This article discusses the pathophysiology and treatment of polycystic ovary syndrome and reports no new results, emphasizing the higher risk of metabolic and cardiovascular issues for affected women.

This study identified a cytochrome P450 enzyme, CYP-pa1 from Pseudonocardia autotrophica, as responsible for the specific hydroxylation of cyclosporin A at the 9th N-methyl leucine, suggesting potential for biotechnological applications.

This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.

This study observed that women with polycystic ovary syndrome showed hormonal changes and higher post-meal lipemia compared to healthy controls, alongside endothelial dysfunction potentially detectable before insulin resistance.

This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.

This study found that activating both PKM2 and Wnt/β-catenin signaling enhanced hair re-growth and HFSCs proliferation in mice, suggesting a potential treatment strategy for alopecia.

This study found that the protein OsUEV1B is essential for maintaining phosphate balance in rice, with Pi deficiency leading to its inhibition and causing overaccumulation of phosphate in mutants.

This review suggests the existence of a new syndrome characterized by keratosis pilaris, ulerythema ophryogenes, and monosomy 18p, emphasizing its potential utility in diagnosing monosomy 18p.

This study found that diphlorethohydroxycarmalol significantly increased prostaglandin $E_2$ synthesis in HaCaT human keratinocytes by upregulating COX-1 and COX-2 expression, suggesting potential benefits from elevated $PGE_2$ production.

This study suggests that the neurosteroid allopregnanolone may play a crucial role in how ethanol affects neurons related to alcohol addiction vulnerability.