Polyphenolization: Hair Browning by Phenolic Adhesion, Ambient Oxygen, and Transition Metals
June 2025
in “
OPAL (Open@LaTrobe) (La Trobe University)
”
New to Keratin? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that a synthetic polyphenol, dimeric 1,2,4-benzenetriol (diBTO), can coat gray hair and gradually oxidize, creating a resistant brown layer similar to apple browning, which offers a practical hair dyeing solution that withstands washing and reduces the need for long dyeing sessions. Our plain-language summary of this paper — not a Tressless recommendation.
This study explores a novel hair dyeing method using polyphenol coating and oxidation, similar to apple browning, to achieve a nonwashable brown color on gray hair. The synthetic polyphenol, dimeric 1,2,4-benzenetriol (diBTO), forms a stable layer on hair keratin that resists washing. The oxidation process, enhanced by ambient oxygen and Cu(II) ions, deepens the brown color. Cysteine on the hair surface aids in the rapid application of polyphenols. This method offers a practical solution for maintaining hair color with regular shampooing, reducing the need for long exposure times typical of professional hair dyeing.
