Olfactory Epithelium Regeneration And Homeostasis: Cellular And Molecular Mechanisms And Novel Methodological Advances

    June 2026 in “ Cell Regeneration ”
    Jiaming Qi, Yiqun Yu
    Studysummary This review highlights the roles of key transcription factors and signaling pathways in regulating olfactory epithelium regeneration, discussing recent advances in single-cell and spatial transcriptomics as well as organoid models to enhance understanding of olfactory regeneration mechanisms.
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    Research cited in this study 2

    1. IL-17a Induces Age-Related Olfactory Dysfunction by Impairing Regeneration and Promoting Respiratory Metaplasia in Mice Nature Communications · 2025
    2. LGR5 Is a Conserved Marker of Hair Follicle Stem Cells in Multiple Species and Is Present Early and Throughout Follicle Morphogenesis Scientific Reports · 2022