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PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

D-OCT shows increased blood vessel growth in response to tissue damage in Frontal Fibrosing Alopecia and is useful for diagnosis and monitoring.

Blocking JAK-STAT5 signaling in mice leads to hair growth.

Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

WNT signaling is crucial for skin development and healing.

Exosomes could be a promising way to help repair skin and treat skin disorders.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

Dermal EZH2 controls skin cell growth and differentiation in mice.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Dermal EZH2 controls skin cell development and hair growth in mice.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Epigenetic factors play a crucial role in skin health and disease.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Mice without certain skin proteins had abnormal skin and hair development.

The research found genes that may protect certain scalp cells from hair loss.