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Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

Women with PCOS often have metabolic issues like insulin resistance and a higher risk of diabetes and abnormal lipid levels.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

TLR3 activation helps improve skin and hair follicle healing in mice.

Women with PCOS often have irregular periods, a higher chance of infertility and miscarriages, and may improve fertility with lifestyle changes and treatment.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

Hyperthyroidism can hide signs of high androgen levels in females.

Women with PCOS are much more likely to have sleep problems and should be checked for them.

Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.

Hair growth can be induced by transplanting certain cells, but these cells lose their properties during culturing. The best cell interaction happens in a liquid medium under gravity, and using collagen doesn't help. Future research could focus on using growth factors to stimulate these cells.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Hair growth is cyclic and influenced mainly by local factors.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.