Tackling Polycystic Ovary Syndrome

January 2001 in “ Drug and therapeutics bulletin ”

TLDR The document concludes that management strategies for PCOS are important due to its common occurrence and associated health risks.

The document from January 1, 2001, discusses the prevalence and characteristics of polycystic ovary syndrome (PCOS) in the UK, where up to one-third of women have polycystic ovaries, and approximately one-third of these women exhibit PCOS. PCOS is typically defined by the presence of polycystic ovaries along with symptoms such as hirsutism, male-pattern baldness, acne, irregular menstrual cycles, obesity, and elevated levels of testosterone and/or luteinising hormone. The review also highlights the associated metabolic issues with PCOS, including insulin resistance and abnormal serum lipid levels, which increase the risk of diabetes mellitus in affected women. The document aims to review the management strategies for women with PCOS.

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6 / 21 results

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 57 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

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Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

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OP is experiencing significant hair loss despite GFC and PRP treatments and has abnormal lab results. They are advised to consult a hair-focused dermatologist for further evaluation.

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in Research/Science 41 upvotes 5 months ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

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Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

Related Research

1 / 1 results

research Hirsutism Scoring in Polycystic Ovary Syndrome: Concordance Between Clinicians' and Patients' Self-Scoring

10 citations , June 2010 in “Fertility and Sterility”

Patients with PCOS tend to score their hirsutism higher than clinicians, making self-scoring less useful for diagnosis.