36 citations
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May 2005 in “BMC dermatology” This study found that topical diphenylcyclopropenone was effective in treating severe alopecia areata but had a high relapse rate and was often accompanied by side effects like eczema and lymphadenopathy.
44 citations
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February 2015 in “Journal of the American Academy of Dermatology” This study found that combination therapy with diphenylcyclopropenone and anthralin was more effective for complete hair regrowth in chronic extensive alopecia areata than diphenylcyclopropenone alone, despite more common side effects.
7 citations
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December 2022 in “Skin Appendage Disorders” This study found that among anti-TNF-α agents, certolizumab is the least likely to cause paradoxical reactions such as psoriatic alopecia and appears to be an effective and safe option for managing psoriasis and PsA while minimizing these risks.
1 citations
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June 1959 in “A M A Archives of Dermatology” In this study, treatment of alopecia areata, totalis, and universalis with methyl prednisolone and ACTH injections resulted in complete regrowth in 62% of male and 58% of female patients.
July 2024 in “Journal of Investigative Dermatology” 20 citations
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June 2019 in “Archives of dermatological research” In this study, combination therapy with DPCP and anthralin promoted hair regrowth in 40.62% of alopecia areata patients who were unresponsive to DPCP alone, with response improving over longer treatment durations.
29 citations
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July 2019 in “Dermatologic Therapy” This report describes two patients with atopic dermatitis receiving dupilumab, where one experienced healing of alopecia areata and the other developed it, illustrating the drug's varied effects.
January 2003 in “Journal of Practical Aesthetic and Plastic Surgery” This study found that intralesional Diprospan injections and high-dose intravenous methylprednisolone may be effective for treating longstanding multifocal alopecia areata, with variable hair regrowth observed among patients.
7 citations
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July 2018 in “Journal of Functional Biomaterials” This study evaluated a new anti-baldness product, IPSTiC patch hair, designed to treat androgenetic alopecia, and reported that it effectively inhibits NO radical and 5α-reductase activity while maintaining safety and stability, suggesting its potential for topical use.
September 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study, involving a retrospective analysis of 24 patients in France, found that paradoxical psoriasiform alopecic reactions on the scalp associated with TNFα-targeted therapies for inflammatory bowel disease are rare yet non-scarring, with all patients achieving complete hair regrowth within two months after treatment adjustments.
1 citations
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October 2015 in “The American journal of gastroenterology” This study reported two cases where infliximab-associated psoriasiform alopecia resolved with significant hair regrowth after stopping infliximab and using potent topical steroid treatment.
4 citations
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October 2013 in “Botanics Targets and Therapy” In this animal study, a herbal preparation demonstrated moderate anti-inflammatory and immunomodulating properties, suggesting its potential usefulness for preventing and treating alopecia.
16 citations
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January 2019 in “Skin appendage disorders” This study used a network meta-analysis to compare alopecia areata treatments, finding that intralesional corticosteroids are most effective for mild cases, while diphenylcyclopropenone ranks highest for moderate to severe cases; further research on oral tofacitinib is needed.
April 2023 in “Journal of Investigative Dermatology” This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.
20 citations
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January 2024 in “Journal of the European Academy of Dermatology and Venereology” This study conducted a meta-analysis and found that among therapies for alopecia areata, baricitinib_4 mg was most likely to be effective, followed by ritlecitinib and ivarmacitinib, while other treatments like dupilumab and secukinumab were less effective.
20 citations
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August 2019 in “Frontiers in immunology” This review discusses the potential of biologics for treating various skin disorders, highlighting positive outcomes in conditions like pityriasis rubra pilaris and lupus, while noting mixed efficacy in others like alopecia areata; it reports no new clinical results.
26 citations
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June 2003 in “PubMed” In this study, severe hair loss occurred in PKC epsilon transgenic mice treated with DFMO during skin tumor prevention, highlighting a link between polyamine biosynthesis, hair follicle maintenance, and metastasis suppression.
3 citations
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August 2019 in “PubMed” This study found that topical corticosteroid foams are effective and generally preferred by patients for a variety of corticosteroid-responsive skin conditions, demonstrating significant clinical benefits such as improved psoriasis symptoms and hair regrowth in alopecia areata compared to traditional forms.
January 2019 in “Figshare” This study found that intralesional corticosteroids were most likely to produce a response in mild alopecia areata, while diphenylcyclopropenone was top-ranked for moderate to severe cases.
January 2016 in “Çağdaş tıp dergisi” This article reports a case of alopecia areata that responded positively to treatment with topical 1% pimecrolimus.
1 citations
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July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
4 citations
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January 2009 in “Indian Journal of Dermatology, Venereology and Leprology” This archived website overview discusses Bioline International's role in reducing the knowledge gap by hosting peer-reviewed journals from developing countries but presents no new research findings.
January 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This study examined the effectiveness of FT-Raman spectroscopy for detecting polymorphism in Lamivudine and Finasteride, highlighting its advantages over other methods due to its capability to provide sharp, well-resolved spectral bands and reduced sampling issues.
17 citations
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November 2009 in “Dermato-endocrinology” This study found that a series of three monthly courses of medium-dose prednisolone pulse therapy was effective and well tolerated in most patients with active, multifocal alopecia areata but not in those with totalis/universalis.
October 2021 in “Journal of Investigative Dermatology” This study found no significant difference in the seroconversion rate of SARS-CoV2 IgG between patients with Immune Mediated Inflammatory diseases undergoing Targeted Immune-Modulating Therapies and those on conventional systemic treatment.
May 2023 in “Elsevier eBooks” This article discusses the use of immunomodulatory therapies for treating alopecia areata or frontal fibrosing alopecia that occur alongside androgenetic alopecia, but it reports no new results.
8 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case study describes the successful treatment of a 13-year-old girl with relapsing polychondritis and autoimmune symptoms using co-trimoxazole, highlighting its potential role in managing autoimmune diseases.
5 citations
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January 2024 in “Therapeutic Advances in Hematology” This report suggests an association between eosinophilic folliculitis and sustained complete response in a Sézary syndrome patient treated with mogamulizumab, although regular monitoring is necessary to prevent relapse.
2 citations
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November 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This case report observed that oral tofacitinib treatment resolved both alopecia universalis and plaque psoriasis in a patient, possibly by targeting shared inflammatory pathways.
8 citations
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January 2017 in “Korean Journal of Physiology and Pharmacology” This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.