Dupilumab And Alopecia: A Janus Effect

    July 2019 in “ Dermatologic Therapy
    Cataldo Patruno, Maddalena Napolitano, Maria Ferrillo, Gabriella Fabbrocini
    TLDR Dupilumab can both heal and cause hair loss.
    The paper discussed the dual effects of dupilumab, an anti-IL4/IL13 monoclonal antibody, on patients with atopic dermatitis (AD) and alopecia areata (AA). While some patients experienced healing of AA during dupilumab treatment for AD, others developed AA as a side effect. The authors reported two cases illustrating these contrasting outcomes, highlighting the complex and unpredictable nature of dupilumab's impact on AA.
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