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    Glossary Pluripotency Genes

    enable cells to develop into any cell type

    Pluripotency genes, also known as pluripotency factors, are specific genes that enable a cell to develop into any type of cell in the body. These genes, such as Oct4, Sox2, and Nanog, are crucial for maintaining the self-renewal and undifferentiated state of stem cells, allowing them to potentially regenerate damaged tissues or organs.

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    1. Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes Development · 2017 · 160 citations
    2. Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells Cellular reprogramming · 2014 · 3 citations
    3. LB1606 Retainability of pluripotency and viability of multilineage-differentiating stress enduring (Muse) cells after repeated cryopreservation. Journal of Investigative Dermatology · 2018 · 1 citations
    4. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    5. 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing Journal of Investigative Dermatology · 2024
    6. 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks 2022
    7. Identification of key pathways and genes that regulate cashmere development in cashmere goats mediated by exogenous melatonin Frontiers in veterinary science · 2022 · 3 citations
    8. Hair follicle associated pluripotent (HAP) stem cells jump from transplanted whiskers to pelage follicles and stimulate hair growth Scientific Reports · 2022
    9. Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage 2010 · 101 citations
    10. The Opportunities and Challenges regarding Induced Platelets from Human Pluripotent Stem Cells Stem Cells International · 2021 · 2 citations
    11. Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells Nature communications · 2014 · 99 citations
    12. First symposium on natural gene therapy of the skin Experimental dermatology · 2012 · 9 citations
    13. 516 Functional annotation of genes underlying hair disorders 2017
    14. Use of human induced pluripotent stem cell-derived CD271+CD90+ mesenchymal stem cells for the generation of hair inductive dermal cells Journal of dermatological science · 2016
    15. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    16. Analysis of hidradenitis suppurativa–linked mutations in four genes and the effects of PSEN1-P242LfsX11 on cytokine and chemokine expression in macrophages Human Molecular Genetics · 2018 · 25 citations
    17. Feasibility of repairing skin defects by VEGF<sub>165</sub> gene‐modified iPS‐HFSCs seeded on a 3D printed scaffold containing astragalus polysaccharide Journal of Cellular and Molecular Medicine · 2023 · 1 citations
    18. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes Stem Cell Reviews and Reports · 2011 · 91 citations
    19. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    20. Canine Epidermal Neural Crest Stem Cells: Characterization and Potential as Therapy Candidate for a Large Animal Model of Spinal Cord Injury Stem Cells Translational Medicine · 2014 · 17 citations
    21. TGF-β family signaling in stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 132 citations
    22. Skin tissue engineering Stembook · 2009 · 12 citations
    23. Establishment of Tsc2-deficient rat embryonic stem cells International Journal of Oncology · 2015 · 8 citations
    24. Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies Current Pharmaceutical Biotechnology · 2011 · 9 citations
    25. 859 Building a functional niche for hair follicle stem cells Journal of Investigative Dermatology · 2017
    26. 547 CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation Journal of Investigative Dermatology · 2022
    27. 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa Journal of Investigative Dermatology · 2019
    28. 312 CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells Journal of Investigative Dermatology · 2019 · 1 citations
    29. Stem Cells and their Niches Journal of Investigative Dermatology · 2013 · 1 citations
    30. Activation of TLR3 Enhance Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells (PDLSCs) Springer eBooks · 2016 · 3 citations