138 citations
,
June 2019 in “Stem Cells and Development” This review explores the potential of periodontal ligament stem cells for regenerative therapy in periodontium, despite challenges due to their rarity, and reports no clinical results.
25 citations
,
November 2017 in “Molecular Medicine Reports” This study found that PlncRNA‑1 may enhance the proliferation and differentiation of hair follicle stem cells by upregulating the TGF‑β1-mediated Wnt/β-catenin signaling pathway.
20 citations
,
November 2020 in “Stem Cell Research & Therapy” This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.
72 citations
,
November 2012 in “PloS one” This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.
November 2025 in “Journal of Investigative Dermatology” KLHL24-mutant stem cells help understand skin and heart disease.
16 citations
,
April 2000 in “Contact dermatitis” In this report, a 19-year-old Japanese man experienced severe and prolonged urticarial reactions following treatment with diphenylcyclopropenone for alopecia universalis, emphasizing the need for caution with potent sensitizers.
This case report describes a novel mutation in the CDH3 gene in an 11-year-old Iranian boy with sparse scalp hair and macular dystrophy, leading to altered P-cadherin synthesis.
This study found that the Arabidopsis cation chloride cotransporter (CCC1) is crucial for regulating pH and processes in the trans-Golgi-network/early endosome, impacting plant growth and stress responses.
November 2022 in “Journal of Investigative Dermatology” This study provides evidence that ILC1-like cells can induce alopecia areata in previously healthy human hair follicles, challenging the view that it is solely an autoantigen-dependent autoimmune disease.
January 2014 in “生命科学(ISSN1934-7391)” A certain gene variation can affect protein production and is linked to male pattern baldness.
206 citations
,
September 2010 in “PLoS ONE” This study found that using a Picosecond IR Laser (PIRL) on mouse skin led to less tissue damage and scarring compared to conventional surgical lasers and tools.
64 citations
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March 2004 in “Journal of Clinical Investigation” This study found that inhibiting the enzyme ornithine decarboxylase (ODC) prevented UVB-induced basal cell carcinomas in a mouse model, suggesting ODC is a potential target for chemoprevention strategies.
1 citations
,
November 2024 in “Cutis” PLLA injections can cause hair loss and skin issues.
July 1998 in “Proceedings of SPIE” This study found that Low Power Laser therapy may be an effective complementary treatment for scalp alopecia and crural ulcers, showing quicker and potentially better results than conventional treatments.
47 citations
,
September 2012 in “Human molecular genetics online/Human molecular genetics” This study suggests that the interaction between folliculin and plakophilin-4 (p0071) may play a role in folliculin's tumor suppressor function by regulating RhoA signaling, impacting cell migration and junction formation.
May 2024 in “Internattional journal of current innovation in advance research” This review discusses PCOD, highlighting its hormonal abnormalities and contributing factors, such as lifestyle and genetics. The authors emphasized that lifestyle changes and medications are central to effectively managing symptoms and improving fertility in impacted women.
280 citations
,
January 2004 in “The EMBO Journal” AGC2-1 protein is essential for root hair growth in Arabidopsis.
158 citations
,
June 2014 in “Journal of Lipid Research” This review summarizes recent discoveries of GPCRs for lysophosphatidylserine and lysophosphatidylinositol, detailing their roles as lipid mediators, but reports no new experimental results.
9 citations
,
June 2017 in “American journal of ophthalmology. Case reports” This case report identifies a novel CDH3 gene mutation associated with hypotrichosis with juvenile macular dystrophy in a 13-year-old Turkish girl, highlighting implications for future genetic analysis and counseling.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” LIPH mutations cause woolly hair in some Chinese people.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a 26-year-old woman with polycystic ovarian disease and advanced hair loss (Ludwig Grade III) showed reduced hair shedding and improved hair density after four sessions of platelet-rich plasma combined with microneedling, with no reported adverse effects.
February 2022 in “Mediators of Inflammation” This study found that reduced plasma DIAPH1 levels were associated with polycystic ovary syndrome, suggesting DIAPH1 as a potential predictive factor for the condition.
9 citations
,
October 2017 in “Frontiers in plant science” This study found that the peach gene CTG134 mediates auxin-ethylene crosstalk, affecting root hair growth and hormone-regulated processes in plants.
2 citations
,
October 1990 in “The Lancet” Some people have a genetic variation that makes them less effective at breaking down drugs.
September 2023 in “International journal of biological macromolecules” This study found that a chitosan/PDRN nanopolyplex significantly improved diabetic wound healing in rats by enhancing cell proliferation, migration, and antimicrobial activities, suggesting its potential as a therapeutic product.
1 citations
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May 2025 in “BMC Cancer” In this study, the researchers found that different CDK4/6 inhibitors used in treating HR+/HER2- advanced breast cancer have varying safety profiles and impacts on patient quality of life.
62 citations
,
November 2022 in “Acta Pharmaceutica Sinica B” This study reported that an injectable hydrogel based on platelet-rich plasma and laponite improved wound healing in diabetic and normal rats by enhancing angiogenesis and macrophage polarization.
11 citations
,
May 2018 in “Frontiers in plant science” This study found that overexpressing the PCaP2 protein in Arabidopsis enhanced drought tolerance by influencing ABA and SA signaling pathways and regulating root hair growth, suggesting a key role in water deficit response.
December 2004 in “Annales d Urologie” This article examines the PCPT study on whether daily finasteride can reduce prostate cancer incidence, describing its methodology and findings but reporting no new clinical results.
April 2012 in “The FASEB Journal” In this study, researchers observed that knocking down the LPA 4 receptor in zebrafish embryos led to vascular and lymph vessel development abnormalities, including edema and decreased heartbeats.