Safety and Quality of Life of CDK4/6 Inhibitors Therapy for Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer: A Multicenter Cross-Sectional Survey in China

    May 2025 in “ BMC Cancer ”
    Benlong Yang, Zhengkui Sun, Quchang Ouyang … Jiong Wu
    Studysummary In this study, the researchers found that different CDK4/6 inhibitors used in treating HR+/HER2- advanced breast cancer have varying safety profiles and impacts on patient quality of life.
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    Research cited in this study 2

    1. Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force Dermatology for Cancer Patients International Study Cancers · 2023
    2. Fatigue, Alopecia, and Stomatitis Among Patients With Breast Cancer Receiving Cyclin-Dependent Kinase 4 and 6 Inhibitors: A Systematic Review and Meta-Analysis Expert Review of Anticancer Therapy · 2017