The Transcription Factor CEBPB Is a Novel Hub Gene and Multi-Functional Disease Driver in Psoriatic Skin Inflammation

November 2022 in “ Journal of Investigative Dermatology ”

M. Mubarak, M. Jargosch, C. Hillig, Michael P. Menden, K. Eyerich, S. Eyerich

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CEBPB innate lymphoid cells-type 1 ILC1 alopecia areata hair follicles ILC1-like cells NKG2D IFNg immune privilege collapse CD8+ T cell

Studysummary This study provides evidence that ILC1-like cells can induce alopecia areata in previously healthy human hair follicles, challenging the view that it is solely an autoantigen-dependent autoimmune disease.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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