April 2014 in “The FASEB Journal” Platelet-rich plasma therapy can reduce hair loss and enhance hair growth in androgenetic alopecia patients, with no side effects observed.
January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Platelet rich plasma may be beneficial for treating hair loss.
January 2014 in “프로그램북(구 초록집)” Platelet-rich plasma treatments help hair growth in people with hair loss by increasing certain cell growth and protein levels.
May 2013 in “Hair transplant forum international” The congress discussed using growth factors for hair treatments and a workshop focused on female hair loss.
January 2013 in “Italian journal of anatomy and embryology” Platelet Rich Plasma can help human hair grow in a lab setting.
January 2013 in “Otorhinolaryngology clinics : an international journal” PRP shows promise for improving healing and hair growth in cosmetic surgery but results can vary.
January 2013 in “프로그램북(구 초록집)” The study evaluated the efficacy and safety of sequential treatment with platelet-rich plasma (PRP) injection followed by mesotherapy in treating various types of alopecia in males and females aged 20-60. Clinical improvement in hair count and thickness was observed in all patients, with no significant side effects other than mild pain and transient bleeding at the injection or microneedling site. In vitro, PRP demonstrated anti-apoptotic effects by upregulating BCl-2 expressions in cultured dermal papilla cells. The study concluded that this sequential treatment promoted hair growth.
July 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Platelet-rich plasma can potentially increase hair growth and density, but more trials are needed to confirm its effectiveness and safety.
April 2023 in “Journal of Shaheed Suhrawardy Medical College” PRP treatment effectively improves hair density and thickness in people with androgenic alopecia.
April 2023 in “Journal of Investigative Dermatology” This literature review evaluates the effectiveness of Platelet-Rich Plasma (PRP) in treating androgenetic alopecia (AGA), a condition affecting over 60% of the global population and responsible for more than 90% of hair loss disorders. The review analyzed 27 controlled studies and clinical trials from 2012 to 2022, involving over 1,072 subjects who received PRP or control treatments bi-monthly to monthly for 3-6 months. The majority of these studies reported positive outcomes, including increased hair growth, density, diameter, and quantity. However, further research is needed to standardize PRP protocols and explore its potential as a combination therapy for optimal AGA treatment.
March 2023 in “Medica Hospitalia: Journal of Clinical Medicine” PRP is a safe and effective treatment for hair growth in alopecia areata.
PRP treatment mildly to moderately improves hair loss in most men with AGA.
February 2023 in “Journal of Advanced Research” A new method using Platelet-rich Plasma (PRP) in a microneedle can promote hair regrowth more efficiently and is painless, minimally invasive, and affordable.
February 2023 in “International Journal of Biological Macromolecules” January 2023 in “Journal of Cosmetic Dermatology” PRP is effective for treating hair loss, improving hair density, count, and thickness.
January 2023 in “Indian Journal of Dermatology, Venereology and Leprology” Higher platelet counts and activators in PRP improve hair density and thickness in treating hair loss.
January 2023 in “Journal of Dermatological Treatment” The study titled "Successful treatment of hereditary hypotrichosis simplex by platelet rich plasma injection with topical minoxidil 2%" reports a successful treatment approach for hereditary hypotrichosis simplex using a combination of platelet-rich plasma (PRP) injections and topical minoxidil 2%. The treatment led to significant hair growth in patients, demonstrating the potential effectiveness of this combined therapy for managing this genetic condition. The study highlights the promising results of PRP and minoxidil in promoting hair regrowth, providing a new therapeutic option for individuals suffering from hereditary hair loss.
January 2023 in “Aesthetic Plastic Surgery” January 2023 in “Journal of Clinical and Diagnostic Research” Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.
January 2023 in “The Egyptian Journal of Hospital Medicine” The review article examines the role of platelet-rich plasma (PRP) in treating androgenetic alopecia (AGA). PRP promotes stem cell proliferation and differentiation in hair follicles, improving blood flow and regulating angiogenesis. It has antiapoptotic and mitogenic effects that prolong the survival of dermal papillae. The review of clinical studies indicates that PRP therapy is a promising and effective treatment for AGA, with minimal downtime, adverse effects, and safety concerns.
December 2022 in “Scientia Pharmaceutica” PRP is more effective than minoxidil and placebo for treating hair loss.
December 2022 in “Journal of Dermatology Research” Platelet Rich Plasma (PRP) treatment significantly improved Female Pattern Hair Loss in a study, but more trials are needed for confirmation.
December 2022 in “Journal of Clinical Medicine” The study investigated a novel PRP treatment protocol for androgenetic alopecia in 2 male patients, showing significant improvements in hair growth metrics, including a 30-59% increase in the average number of hairs, a 35-53% increase in cumulative hair thickness, and a 14-48% increase in the number of follicular units in the vertex region. The results suggest the new PRP regimen is effective, though further studies with larger sample sizes are needed to confirm these findings.
December 2022 in “Plastic and Reconstructive Surgery” This study evaluated the efficacy of combining platelet-rich plasma (PRP) with basic fibroblast growth factor (PRPF) for treating androgenetic alopecia (AGA). Eighty patients (47 men and 33 women, mean age 28.96 years) participated in a randomized, double-blind, placebo-controlled trial. They were divided into two groups: one received PRPF on one half of the scalp and placebo on the other, while the second group received PRPF on one half and PRP on the other. Treatments were administered three times, one month apart, and hair growth was monitored for six months. Both PRP and PRPF treatments showed significant improvements in hair count, terminal hair, and anagen hair. However, PRPF demonstrated superior efficacy compared to PRP, with significant improvements in hair count, terminal hair, vellus hair, and anagen hair. The study concluded that PRPF is a safe and more effective treatment for AGA than PRP.
December 2022 in “Journal of Investigative Dermatology” Combining PRP and minoxidil improves hair growth and density in treating hair loss.
December 2022 in “Dermatologie pro praxi” Combining PRP, minoxidil, and finasteride significantly improved hair regrowth.
November 2022 in “Frontiers in Medicine” This systematic review assessed the efficacy of platelet-rich plasma (PRP) in treating alopecia areata (AA) and primary cicatricial alopecias (PCAs) by analyzing 32 studies with 621 AA patients and 19 PCA patients. PRP showed promising results in AA, especially in mild cases, with better efficacy than placebo and similar efficacy to intralesional triamcinolone acetonide (TA). PRP also had benefits as an adjunctive treatment. However, its efficacy in PCAs was less clear due to limited studies and variable responses. The review emphasizes the need for more high-quality, randomized controlled trials to confirm PRP's therapeutic potential in these conditions.
November 2022 in “Journal of Nanobiotechnology” This study developed a scalable and high-throughput method for producing an injectable composite system combining platelet-rich plasma (PRP), cell-laden microcarriers, and hydrogels for hair follicle (HF) tissue engineering. The system, tested both in vitro and in vivo, significantly enhanced dermal papilla cell (DPC) proliferation, migration, and HF regeneration. In vivo experiments on mice showed that PRP-loaded microcarriers accelerated hair cycle transition and increased new hair follicle formation, with ~35 HFs and ~12 vessels per site. The findings suggest that this composite system could be a promising approach for treating hair loss and promoting hair growth through sustained release of growth factors and a conducive microenvironment.
October 2022 in “Dermatology practical & conceptual” The study compared the effectiveness of transepidermal delivery of triamcinolone acetonide and platelet-rich plasma (PRP) using either fractional carbon dioxide laser or microneedling in treating alopecia areata. The results indicated that both methods were effective in promoting hair regrowth, with PRP showing slightly better outcomes. The study involved a significant number of participants, enhancing the reliability of the findings. The conclusion suggests that both treatments are viable options for alopecia areata, with PRP potentially offering a slight advantage.
October 2022 in “MedNEXT Journal of Medical and Health Sciences” PRP effectively treats hair loss, especially when combined with microneedling or minoxidil.