A Randomized, Double-Blind, Placebo-Controlled, Split Patch Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

    July 2018 in “ International Journal of Research in Medical Sciences ”
    Bushra Khan, Ramesh Sharma, Milind Borkar
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    TLDR Platelet rich plasma was slightly more effective than no treatment for hair loss in alopecia areata patients.
    In a randomized, placebo-controlled, split patch study conducted 5 years ago, 30 patients with Alopecia Areata (AA) were treated with 1-1.5ml of autologous Platelet Rich Plasma (PRP) made by double spin method into half the bald patch area and the other half with placebo. The treatment was administered once a month for 3 months. The results showed that the administration of autologous PRP led to observable improvement in 20% of the cases treated with PRP and only 3.3% of control cases. The study concluded that PRP was found to be minimally effective, but more efficacious than no treatment, and safe for AA patients.
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