15 citations
,
August 2019 in “Dermatologic Therapy” This letter details a case report on platelet-rich plasma treatment for a patient with treatment-resistant frontal fibrosing alopecia, but it does not provide new clinical results.
15 citations
,
March 2018 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma combined with other hair restoration therapies significantly increased hair density in patients with androgenetic alopecia, though it did not statistically affect hair shaft diameter.
12 citations
,
June 2020 in “Journal of The American Academy of Dermatology” This article discusses platelet-rich plasma therapy for cicatricial alopecias like lichen planopilaris and reports no confirmed new clinical results; the authors highlight ongoing uncertainty about its effectiveness and potential risks.
12 citations
,
June 2019 in “Clinics in dermatology” This review highlights the use of platelet-rich plasma in dermatology for skin and hair treatments but reports no new clinical results, emphasizing the need for larger studies to validate its effectiveness.
10 citations
,
May 2016 in “Journal of Dermatological Science” This study found that PDGF-BB affects human melanocytes differently depending on their differentiation stage, stimulating melanoblast proliferation but inhibiting melanocyte proliferation while promoting their differentiation.
6 citations
,
March 2021 in “Journal of Cosmetic Dermatology” In this study, platelet-rich plasma treatment improved hair regrowth and characteristics in mice and showed therapeutic efficacy in Chinese patients with androgenetic alopecia.
4 citations
,
November 2020 in “Journal of The American Academy of Dermatology” This article discusses the factors driving the platelet-rich plasma market in dermatology and reports no clinical results; it highlights the need for more affordable and accessible treatments.
4 citations
,
October 2020 in “JAAD Case Reports” This article discusses the potential use of platelet-rich plasma as a treatment for vitiligo, but reports no new clinical results; further investigation is needed.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma with microneedling for hair loss was mostly well tolerated, but some patients experienced mild side effects like scalp itching, transient hair shedding, and lymphadenopathy.
3 citations
,
May 2017 in “Dermatologic Surgery” PRP may help treat female hair loss, but more research needed.
3 citations
,
January 2016 in “South African family practice” This review suggests that platelet-rich plasma shows potential for improving alopecia areata and skin rejuvenation, but more research is needed as evidence primarily supports short-term outcomes in orthopaedic applications.
1 citations
,
August 2020 in “Journal of The American Academy of Dermatology” This letter discusses the variability in platelet-rich plasma preparation for androgenetic alopecia treatment and highlights that different methods yield varied platelet concentrations but not significant differences in growth factor secretion per platelet.
April 2020 in “Journal of The American Academy of Dermatology” This letter highlights concerns about transient lymphadenopathy as a potential adverse effect of platelet-rich plasma combined with microneedling for alopecia, emphasizing the need to understand its underlying cause.
270 citations
,
March 2012 in “Dermatologic Surgery” This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.
136 citations
,
April 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
87 citations
,
March 2020 in “Australian Dental Journal” This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.
63 citations
,
October 2013 in “Dermatologic Surgery” In this study using a mouse model, the researchers found that platelet-rich plasma significantly increased the number of newly formed hair follicles and decreased the time for hair formation compared to no treatment.
58 citations
,
January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
55 citations
,
September 2017 in “Journal of Cosmetic Dermatology” This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.
48 citations
,
May 2023 in “Nature Communications” In a study on muscle regeneration in mice, researchers found that platelet-secreted CXCL7 is crucial for recruiting neutrophils to injury sites, aiding early muscle repair and optimal regrowth, suggesting potential therapeutic uses for boosting muscle healing.
39 citations
,
November 1987 in “Clinica Chimica Acta” Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.
31 citations
,
January 2019 in “Journal of Cutaneous Medicine and Surgery” This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.
18 citations
,
July 2020 in “Journal of The American Academy of Dermatology” This study found that PRP injections using the Eclipse system significantly improved hair density and caliber in women with androgenetic alopecia compared to saline placebo at 24 weeks.
16 citations
,
January 2021 in “International Journal of Medical Sciences” This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.
13 citations
,
January 2020 in “Experimental Dermatology” This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.
12 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
12 citations
,
April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
5 citations
,
December 2020 in “Wound Repair and Regeneration” This review discusses the challenges and perspectives of using platelet-rich plasma in burn and wound management, noting that current variability in its composition and application prevents clear conclusions on its effectiveness.
4 citations
,
April 2025 in “Scientific Reports” This study found that platelet-rich plasma can transiently inhibit bacterial growth in vitro against multidrug-resistant strains from diabetic foot infections, although its efficacy diminished over time and did not affect biofilm formation.
2 citations
,
November 2023 in “Curēus” This review explores platelet-rich plasma's role in wound healing and discusses its potential as a broadly applicable therapeutic option, but it reports no new clinical results.