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Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Skin aging reflects overall body aging and can indicate internal health conditions.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Cell aging can be both good and bad for tissue repair.

A man with multiple autoimmune diseases developed liver injury from azathioprine, but his liver improved after stopping the drug.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

A new mutation in the HR gene causes hair loss in a specific family.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Hair loss is significantly linked to lower levels of certain genes in hair follicles.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.