Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.

The document provides a quiz for physicians to earn continuing medical education credits in facial plastic surgery.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This study identified a moderately high prevalence of PCOS and significant associations with factors like hyperprolactinemia and menstrual irregularities in the sample, emphasizing the importance of awareness and early diagnosis to potentially reduce PCOS burden.

This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.

This study observed that keratosis pilaris is the most prevalent follicular keratotic disease, especially in adolescent and young adult females, and emphasized the key role of dermoscopy and histopathology in distinguishing it from other similar disorders and aiding in diagnosis.

This study found that while educating healthcare providers significantly improved their knowledge of polycystic ovarian syndrome, it did not lead to better diagnosis or management outcomes in a free clinic setting.

This case series highlights the real-world challenges and experiences of US healthcare providers using pegvaliase for phenylketonuria treatment, emphasizing patient education on adverse events and dietary changes, and tailored titration schedules, while reporting that most patients achieved treatment efficacy despite initial adverse events.

This study found that many adolescent girls in Pakistan were unaware of their PCOS symptoms, which are associated with a high prevalence and may be linked to dietary habits affecting menstrual cycles.

This study reported that a significant number of young women in Pakistan may unknowingly have PCOS, with many experiencing irregular periods, weight gain, and increased cravings potentially linked to dietary habits.

This study investigated the histopathology of ectodermal dysplasia/skin fragility syndrome, identifying specific skin and hair abnormalities associated with PKP1 gene mutations in two young female patients.

This Health Policy report outlines the creation of evidence-based clinical practice guidelines and referral pathways for managing dermatological conditions in Pakistan's primary care setting, aiming to standardize care and improve patient outcomes.

This study provides evidence that ILC1-like cells can induce alopecia areata in previously healthy human hair follicles, challenging the view that it is solely an autoantigen-dependent autoimmune disease.

This study found that CLK1 is necessary for epidermal differentiation but does not affect sebocyte differentiation in a telogen skin stem cell line.

This study observed that epidermal-specific deletion of aPKCλ in mice disrupts hair follicle stem cell quiescence, leading to altered hair follicle cycling and skin anomalies.

In this study, long-pulsed 755-nm alexandrite laser treatment for keratosis pilaris significantly improved skin roughness and redness, as well as follicular plug reduction, with good safety and patient satisfaction compared to a moisturizing lotion alone.

In this study, researchers found multiple somatic mutations and copy number variations in a patient with Cronkhite-Canada syndrome, providing novel insights into its potential genetic mechanisms.

This study presents cases of paraproteinemic keratopathy associated with multiple myeloma and MGUS, highlighting varied treatment responses and the need for long-term follow-up to better understand disease progression and management.

This review discusses recent advancements in the management and diagnosis of primary cicatricial alopecias but reports no new clinical results; emerging insights suggest sebaceous gland dysfunction may play a role in their etiopathogenesis.

This review discusses the state-of-the-art knowledge on pseudoxanthoma elasticum, summarizing recent advancements in genetics, pathomechanisms, and potential treatments but reports no new clinical findings.

This study suggests that KRTAP2-3 may serve as a novel biomarker to identify cells in the polyaneuploid cancer cell state, which is linked to therapy resistance and poor prognosis in prostate cancer.

This update of the 2023 International Guideline for PCOS offers refined diagnostic criteria and management recommendations, emphasizing evidence-based care, but notes that research quality remains low to moderate.

In this study, researchers identified a novel congenital skin disorder in Chesapeake Bay retrievers, linked to a plakophilin-1 deficiency due to a genetic mutation, marking the first known occurrence in an animal species.

This study found that PRP injections may safely improve penile curvature and PDQ scores in men with stable-phase Peyronie's Disease, although the curvature reduction observed was not enough to determine long-term clinical significance.

This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.

In this study, DataDerm revealed that from 2016 to 2022, a majority of patients diagnosed with keratinocyte carcinoma were male, predominantly white, and commonly between 56-75 years old, with most living in urban areas and having a history of non-melanoma skin cancer.

This study found that Polycomb repressive complex 1 is crucial for skin development and stem cell specification, influencing gene activity beyond its known repressor functions.

This consensus paper reviews current challenges and recommendations for diagnosing and treating polycystic ovary syndrome, highlighting the utility of the Rotterdam criteria for adults and different criteria for teenagers without requiring polycystic ovaries.

This review from the 2013 Keogh Review found that non-surgical cosmetic interventions in the UK are largely unregulated, leaving patients with little protection or recourse.

This study found that aPKCλ, but not aPKCζ, plays a critical role in maintaining hair follicle stem cell populations and promoting wound healing in the epidermis.