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This study reported that UVR induced PKCε phosphorylation of Stat3 in transgenic mice, suggesting a role in enhancing sensitivity to UVR-related skin cancer development.

This study developed a mouse model lacking keratin 16 to replicate palmoplantar lesions, which may help uncover the molecular mechanisms driving these lesions in pachyonychia congenita and focal non-epidermolytic palmoplantar keratoderma.

This study found that in a sample of girls and adolescents aged 15–24 years, the prevalence of PCOS was 22.5% according to the Rotterdam criteria.

In this study, patients with keratosis pilaris exhibited significant quality of life impairment, with histopathology and dermoscopy revealing consistent skin and hair changes.

This study found that among 52 classification tools on the Clinical Knowledge Summaries website, 46% lacked strong guidance for their use in managing conditions, suggesting that nearly half of the tools may not be useful for clinical decision-making.

This study found that a continuing education program significantly improved rural nurse practitioners' knowledge about assessing, diagnosing, and managing PCOS.

This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.

This article reviews the potential applications of Point of Care procedures in radiology, discussing their ability to enhance the speed of diagnosis and treatment but does not report new results.

This study found that certain keratin gene mutations associated with pachyonychia congenita are linked to altered enamel structure and increased risk of dental caries.

This review analyzes the mnemonic MY PCOS, exploring diagnosis and treatment strategies for the metabolic, cosmetic, and reproductive complications of polycystic ovary syndrome, without reporting new clinical findings.

This study found that sulfated CCK octapeptide reduces psoriasis-like skin inflammation in mice, suggesting a new pathophysiological role for CCK in regulating epidermal inflammation.

This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.

This article describes Amy Senior's evolving views on the Joint Council for Cosmetic Practitioners and reports no new research findings.

This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.

The Exfoliate-Dissolve-Repair skincare approach may effectively treat keratosis pilaris and reduce the need for corticosteroids.

This study found that young females in Punjab, Pakistan, showed increased prevalence of PCOS symptoms, yet most were unaware of PCOS, suggesting a need for enhanced educational efforts.

This study found that most participants had limited awareness of PCOS and its major risk factors, underscoring a need for increased education on the condition.

This research reports that KCV and its palmitoylated derivatives show strong effectiveness in strengthening hair proteins, indicating their potential for use in advanced hair care products.

This article provides an overview of keratosis pilaris, discussing its different variants, possible pathogenesis, and treatment options, without reporting new clinical results.

This review discusses the diagnosis and treatment strategies for polycystic ovary syndrome, particularly using the "MY PCOS" mnemonic, and reports no new experimental results.

This study reported that 12% of female Qassim University students had been diagnosed with PCOS, with misconceptions about the condition and treatments observed despite high awareness.

This commentary explores the role of PCSK9 as a target for drug development, underscoring that individuals with PCSK9 loss-of-function mutations experience significantly lowered LDL cholesterol levels and reduced coronary events, suggesting that full inactivation of PCSK9 is effective and safe.

This study found strong evidence linking a keratin gene anomaly to pachyonychia congenita, supporting its role in affecting skin, nails, hair, and mucosa.

This review discusses primary cicatricial alopecias, detailing their classification, pathogenesis, clinical features, histopathologic findings, and treatment, without reporting new experimental results.

This study found that the new cocrystal formulation KET-PABA improved the antimycotic efficiency of ketoconazole and induced an anti-inflammatory response without causing skin sensitization in mice.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

This observational study conducted at Kushtia Medical College explored the socio-demographic and clinical profiles of 100 women with PCOS, highlighting that a significant number of these patients experienced infertility, dysmenorrhea, and metabolic abnormalities, suggesting a need for timely therapeutic interventions.

In this study, researchers found that inhibiting IKKα in patient-derived CCS tumour models reduces tumour viability, supporting the potential for topical IKKα inhibitors as a treatment for CCS.