Targeting Noncanonical Nuclear Factor Kappa B Signaling in CYLD Cutaneous Syndrome by Selective Inhibition of IκB Kinase Alpha

    Kirsty Hodgson, Joseph Inns, Gary Reynolds … Neil Rajan
    Studysummary In this study, researchers found that inhibiting IKKα in patient-derived CCS tumour models reduces tumour viability, supporting the potential for topical IKKα inhibitors as a treatment for CCS.
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