research XEDAR activates the non-canonical NF-κB pathway
This study found that the XEDAR receptor can activate the non-canonical NF-kB pathway involving p100 processing, which is regulated by interactions with TRAF proteins and specific kinases.
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research Targeting noncanonical nuclear factor kappa B signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha
In this study, researchers found that inhibiting IKKα in patient-derived CCS tumour models reduces tumour viability, supporting the potential for topical IKKα inhibitors as a treatment for CCS.
research Application of medicinal plants in several dermatovenerological entities
This review discusses the use of herbal medicinal products for treating chronic skin diseases like vitiligo and psoriasis and reports no new clinical results; the authors emphasize the need for standardized extracts and further research.
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