318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
11 citations,
January 2023 in “BioMed Research International” Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
6 citations,
April 2023 in “Cosmetics” Exosomes could be effective for improving skin health and treating skin diseases.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
January 2022 in “Skin Appendage Disorders” Areata-like lupus can mimic alopecia areata but is a form of cutaneous lupus erythematosus.
November 2023 in “Frontiers in Medicine” The method effectively mimics shaving damage on skin for testing skincare products.
August 2024 in “Indian Journal of Skin Allergy” Stem-cell therapy shows promise for skin conditions but needs more research.
April 2019 in “Journal of Investigative Dermatology” Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
2 citations,
May 2011 in “British Journal of Dermatology” Pellagra, caused by niacin deficiency and presenting with photosensitivity, should be considered in patients with relevant symptoms and risk factors.
71 citations,
March 1995 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections for alopecia biopsies improves diagnosis without extra cost.
19 citations,
October 2011 in “Clinics in Dermatology” New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
2 citations,
July 2012 in “InTech eBooks” People with alopecia areata often have thyroid autoimmunity.
136 citations,
May 2016 in “Phytotherapy Research” Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
28 citations,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
12 citations,
September 2003 in “Current paediatrics” Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.
10 citations,
August 2016 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Vitiligo patients often have nail problems, so checking their nails is important.
6 citations,
November 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
April 1963 in “Archives of Dermatology” Dermatological conditions are complex and treatments often have mixed results.
58 citations,
April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
34 citations,
July 1987 in “The Journal of dermatologic surgery and oncology” Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
21 citations,
April 2010 in “Veterinary Dermatology” Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
March 2019 in “Journal of Investigative Dermatology” Seborrheic dermatitis is influenced by diet, genetics, and psychological factors.
9 citations,
January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
3 citations,
March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
22 citations,
January 2012 in “Mediators of inflammation” Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
January 2023 in “TNOA journal of ophthalmic science and research” Minoxidil may cause vision problems.
2 citations,
July 2009 in “Mayo Clinic Proceedings” A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.