Development of a Novel In Vitro Strategy to Understand the Impact of Shaving on Skin Health: Combining Tape Strip Exfoliation and Human Skin Equivalent Technology
November 2023
in “
Frontiers in Medicine
”
shaving skin health tape strip exfoliation human skin equivalent technology inflammatory effects barrier damage epidermal proliferation cytokine production barrier function shaving foam moisturizers exfoliation skin model inflammation skin barrier skin growth immune response skin protection shaving cream skin lotion
TLDR The method effectively mimics shaving damage on skin for testing skincare products.
The study developed an in vitro method using tape strip exfoliation and human skin equivalent (HSE) technology to simulate the skin barrier damage caused by shaving. Results showed that tape stripping effectively induced barrier dysfunction, increased transepidermal water loss (TEWL), epidermal thickening, and elevated pro-inflammatory cytokines, mimicking the effects of shaving. The model demonstrated robustness and reproducibility, making it suitable for screening shaving regimens and their effects on skin health. The findings support the use of this platform for in-depth biological analysis and high-throughput screening of shaving-related skincare products.
