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Research

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research 595 In vitro evaluation of skin distribution and human dermal papilla cells proliferation for minoxidil 5% topical lotion hydrogel

July 2022 in “Journal of Investigative Dermatology”

This study found that a new alcohol-free minoxidil hydrogel formulation showed comparable in vitro efficacy and skin absorption to the commercial minoxidil product for treating androgenetic alopecia.

research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream

August 2021 in “Institutional Repositories DataBase (IRDB)”

This study found that rubbing the skin increased caffeine permeation significantly, while rhododendrol showed no enhancement from rubbing, likely due to different distribution patterns in the skin layers.

research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream

1 citations , July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin”

This study found that rubbing significantly increased skin permeation of caffeine but not rhododendrol, with the direction of rubbing playing a crucial role in caffeine's enhancement.

research The Anti-atopic Lotions Containing Fucoidan Extracted from Ecklonia Cava Impact on Hairless Mice Atopic Dermatitis Skin

April 2011 in “한국생물공학회 학술대회”

This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.

research Immunomorphological features of women’s skin with androgenetic alopecia in the treatment of plasma enriched with platelets in combination with topical minoxidil 2 % lotion

December 2021 in “Journal of V. N. Karazin Kharkiv National University: Series Medicine”

In this study, treatment with platelet-rich plasma combined with 2% minoxidil was associated with normalization of immunohistochemical markers in patients with stage I-II androgenetic alopecia, suggesting potential for long-term therapeutic effects.

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Community Join

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community How do you guys apply min with an intensive skin care routine?

3 upvotes 7 years ago

The conversation is about the order of applying minoxidil in a skincare routine, specifically whether to apply it before or after witch hazel and moisturizer. The user is concerned about the lotion interfering with minoxidil absorption.

community Recommended lotion for irritated scalp?

4 upvotes 6 years ago

A user seeks a lotion for an inflamed, itchy scalp caused by DHT, asking for options that promote blood flow and contain hair vitamins like caffeine and biotin. Another user suggests using a mix of mustard oil and coconut oil.

community How to treat skin when using minoxidil?

6 upvotes 6 years ago

Minoxidil may cause skin issues like wrinkles and dark undereyes, possibly due to alcohol content. Alternatives include collagen supplements, vitamin C, and skincare products; some users prefer finasteride for hair loss without these side effects.

community Topical Metformin for Hair Transplant donor area skin/hair regeneration?

4 upvotes 1 year ago

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

community Scalp feels worse than ever, dried skin, inflammation or perhaps plaque?

4 upvotes 1 month ago

The conversation discusses a user's worsening scalp condition, possibly seborrheic dermatitis, despite using keto shampoo. Suggestions include using MCT C8 oil, adjusting diet by reducing carbs and sugars, and consulting a dermatologist.

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Learn

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learn Hydrocortisone

Mild corticosteroid used on the skin and scalp

How do you safely apply hydrocortisone cream or lotion to the scalp without overusing it? US over-the-counter hydrocortisone labels say to apply it no more than three or four times a day and to stop and ask a doctor if symptoms last more than seven days; labels in other countries differ. The scalp absorbs corticosteroids more than most skin, so prolonged use raises the risk of thinning skin.

learn Glycerin

Is glycerin helpful for treating dry, irritated scalps that may lead to hair shedding? Glycerin improved hydration in small studies on body skin and, in one multi-ingredient lotion, on the scalp; there is no evidence it reduces hair shedding.

learn Castor oil

Thick plant oil used in hair care

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid improved hydration of facial skin in trials. It has not been tested on the scalp.

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