Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation
October 2012
in “
Veterinary Pathology
”
alopecia hyperpigmentation scaling hyperthermia lymphadenomegaly anemia thrombocytopenia proteinuria antibodies lymphocyte-rich interface dermatitis folliculitis follicular destruction chronic cutaneous lupus erythematosus systemic lupus erythematosus autoimmune alopecia hair loss skin darkening skin scaling fever swollen lymph nodes low red blood cells low platelets protein in urine lymphocyte-rich skin inflammation hair follicle inflammation hair follicle destruction chronic skin lupus systemic lupus immune system hair loss
TLDR A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.
An adult castrated male Doberman Pinscher presented with bilaterally symmetrical alopecic patches and reticulated hyperpigmentation, which were later associated with systemic lupus erythematosus (SLE). Histological examination revealed lymphocyte-rich interface dermatitis and mural folliculitis, consistent with chronic cutaneous lupus erythematosus (CCLE). Despite treatment with prednisone, the dog's condition worsened, leading to euthanasia. This case highlighted a unique alopecic variant of CCLE in dogs, expanding the understanding of lymphocyte-mediated autoimmune alopecias.
