1 citations
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June 2021 in “Journal of pharmacopuncture” This study found that while CBD did not change gene expression including β-catenin in hair follicles, it restored decreased β-catenin expression in dermal papilla cells affected by testosterone or PMA, suggesting a potential modulating function on alopecia.
9 citations
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December 2021 in “Molecules” This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.
3 citations
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January 2025 in “Journal of Natural Products” In this study, researchers isolated new compounds from the plant *Calanthe cardioglossa* and found that five of these compounds, particularly calancardin B, significantly reduced TNF-α levels in immune cells relevant to multiple sclerosis, suggesting potential for immunomodulatory effects.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that herbal cosmetics offer diverse biological benefits, including antioxidant, antibacterial, and moisturizing effects, enhanced by advanced formulation methods, while emphasizing the need for more clinical validation and standardized practices to ensure long-term safety and efficacy.
5 citations
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January 2020 in “Research journal of pharmacy and technology” This review explores the potential benefits of non-psychoactive Cannabidiol for reducing stress and pain associated with Polycystic Ovarian Syndrome and reports no new clinical findings.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that cannabinoid receptor type 1 may influence psoriasis development by modulating laminin-511 expression, suggesting a potential target for treatment.
August 2025 in “Biomolecules” This review discusses the potential topical benefits of cannabidiol in dermatology and cosmetics, highlighting its diverse effects and therapeutic roles but reports no new clinical results, emphasizing the need for further research.
January 2002 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.
7 citations
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April 2021 in “Cannabis” In this study, topical CBD significantly increased hair count by 93.5% over six months in individuals with androgenetic alopecia, with no adverse effects reported.
December 2024 in “Plant Science Today” This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.
March 2022 in “Research Square (Research Square)” This case report describes a 15-year-old girl with Alopecia Universalis and psychiatric conditions experiencing hair regrowth after self-medicating with cannabis, suggesting it may have therapeutic potential.
July 2023 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study evaluated the resin oil of Copaifera officinalis L., identifying 64 compounds and developing validated analytical methods for quality control, and formulated a stable pharmaceutical foam, laying groundwork for potential clinical applications of copaiba oil.
9 citations
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June 2021 in “Journal of Inflammation Research” This study found that Euph E and Euri A showed strong anti-inflammatory activity and modulated cytokine and immune functions in macrophages, related to specific signaling pathways.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that herbal cosmetics, incorporating modern technologies and traditional knowledge, offer various biological benefits like antioxidant and anti-aging properties. The authors emphasize the need for further clinical validation and standardized manufacturing processes to ensure their long-term safety and effectiveness.
7 citations
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January 2022 in “Anais Da Academia Brasileira De Ciencias” This study found that essential oils from Hedychium spicatum showed anti-inflammatory, antinociceptive, antipyretic, and antioxidant activities, with site-specific variations in their effectiveness.
76 citations
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February 2015 in “Industrial Crops and Products” This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.
1 citations
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November 2025 in “Journal of Cosmetic Dermatology” This source reports on ongoing clinical trials examining the therapeutic potential of topical CBD for skin conditions like acne, dermatitis, and psoriasis, and emphasizes that upcoming trial results will be crucial in evaluating its effectiveness.
February 2025 in “Processes” This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.
1 citations
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October 2025 in “Journal of Microbiology and Biotechnology” This study suggests that phytochemicals from natural sources could be safer alternatives to conventional treatments for hair loss, as they may activate key pathways involved in hair growth.
15 citations
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June 2019 in “Experimental Dermatology” The authors suggest that the neuroendocrine system of the skin represents a promising target for repurposing drugs, such as cannabidiol and fingolimod, as topical treatments for inflammatory skin diseases.
1 citations
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April 2025 in “Phycology” In this review, researchers highlight recent findings on the cosmeceutical applications of phlorotannins from brown seaweeds, emphasizing their promising bioactive properties since 2020.
3 citations
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April 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.
67 citations
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December 2019 in “PloS one” This study found that beta-caryophyllene enhanced re-epithelialization in cutaneous wounds of female mice, suggesting its potential for improving wound healing through multiple pathways.
28 citations
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September 2021 in “EMBO reports” In this study, researchers used cryo-electron microscopy to reveal how the natural compound osthole inhibits TRPV3 channels by binding to specific sites, changing the channel's conformation.
August 2023 in “Current Pharmaceutical Design” This review discusses the potential use of cannabidiol (CBD) for managing COVID-19 patients, especially for controlling cytokine storms in those with acute respiratory distress syndrome, but reports no new clinical results.
3 citations
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January 2017 in “Revista chilena de nutrición” This review highlights that several clinical and epidemiological studies link a diet high in terpenoid compounds with a decreased risk of prostate cancer, supporting the potential use of terpenoids as therapeutic ingredients in treating this disease.
18 citations
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December 2021 in “Foods” This study explores the potential of seaweeds as a source of bioactive compounds for food, cosmetics, and medical applications, while highlighting concerns about toxic element accumulation and suggesting purification and nanoencapsulation techniques to enhance safety and stability.
This review explores the extraction, characterization, and skin cosmetic effects of phenolic compounds and pigments from marine macroalgae, highlighting their documented benefits for skin health, such as whitening, moisturizing, photoprotection, and anti-aging effects, without adverse health impacts.
January 2015 in “Annual Research & Review in Biology” This review explores the potential of phytotherapeutic molecules and oxidative inhibitors as novel anticancer and chemopreventive agents, reporting no new clinical results while suggesting their promise in drug development.
This study investigated the phytochemicals in Phyla nodiflora leaf extracts and identified n-Hexadecanoic acid, stigmasterol, and beta-sitosterol as promising drug candidates for diabetes, alopecia, cancer, and anti-diuresis, advocating further research into these compounds.