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Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.

Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.

Wnt signaling is crucial for skin development and hair growth.

VDR regulation varies by tissue and is crucial for its biological functions.

SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

SIRT7 protein is crucial for starting hair growth in mice.

Integrin β1 is crucial for liver structure and function, preventing fibrosis.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Gray hair can potentially be reversed, leading to new treatments.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.