4 citations
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July 2020 in “BMC Complementary Medicine and Therapies” This study suggests that human placenta treatment may promote hair regrowth in chemotherapy-induced alopecia by inhibiting apoptosis and encouraging hair follicle proliferation in a mouse model.
2 citations
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December 2024 in “BMC Genomics” In this study, researchers used transcriptome sequencing and bioinformatics analysis to identify important genes and pathways involved in the transition between hair growth phases, offering new insights into hair follicle cycle regulation and development.
2 citations
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April 2018 in “Majalah Obat Tradisional” In this study, the FIII micro emulsion formulation of virgin coconut oil and rice bran oil showed the best results for hair growth, increasing rabbit hair length by 1.26 cm in 18 days.
2 citations
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January 2007 in “Toxicologie Analytique et Clinique” This case study observed a massive lithium overdose in a 38-year-old woman with bipolar disorder, who survived despite extremely high lithium concentrations through continuous venovenous hemodiafiltration.
January 2025 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia” In this study, researchers observed that telogen hair was more prevalent than anagen hair in both male and female agoutis over a one-year period in Teresina-PI, regardless of dry or rainy seasons, with no significant differences in dermal follicular volume between the sexes.
This study investigated the expression of KRTAP6 gene family in Gansu Alpine fine-wool sheep, finding significant expression during the anagen phase and a negative correlation between KRTAP6-1 and KRTAP6-5 expressions with wool fiber diameter and strength.
September 2023 in “Cells tissues organs” In this study, researchers observed that in mice, as they age beyond 200 days, unusual curved hair follicles and increased white hairs emerge, indicating stem cell-related changes in keratinocyte and melanocyte characteristics, providing insights into hair aging processes.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that applying the right mechanical stretch to skin can activate hair stem cells and promote hair regeneration through a pathway involving WNT, BMP-2, and M2 macrophages.
September 2017 in “Journal of Investigative Dermatology” In this study, low-dose 453 nm blue light appeared to enhance hair growth by interacting with specific photoreceptors in the outer root sheath cells.
January 2005 in “Pharmaceutical Journal of Chinese People's Liberation Army” In this study with cultured C_57BL/6J mouse hair follicles, ginseng extract at a concentration of 0.1 mg/ml was reported to best promote hair growth.
January 2003 in “Linchuang pifuke zazhi” In this study, Zingiber coralliaum oil induced premature hair growth in mouse skin during tests, suggesting its potential for managing hair growth disorders.
In this study, patients with systemic lupus erythematosus and generalized non-scarring alopecia exhibited hair loss similar to telogen effluvium, with significant changes observed in the cuticle of telogen hairs.
6 citations
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April 2021 in “Frontiers in Immunology” This study presents the first documented case of dramatic hair regrowth in a systemic lupus erythematosus patient with refractory alopecia following tofacitinib therapy, suggesting a potential new application for JAK inhibitors in difficult-to-treat cutaneous SLE manifestations.
October 2023 in “International journal of rheumatic diseases” This study found that the JAK3/TEC kinase inhibitor ritlecitinib was effective and well tolerated in patients aged 12 and older with alopecia areata, providing a potential systemic treatment option for this condition, especially in cases of significant psychosocial impact.
May 2024 in “Journal of cosmetic dermatology” This study found that while caffeine and adenosine can inhibit hair loss and stimulate hair growth, more research is needed to fully understand the efficacy of shampoo formulations containing specific proportions of these compounds for hair loss treatment and prevention.
December 2022 in “Biochemical and Biophysical Research Communications” This study found that HtrA2 inactivation in mnd2 mice is associated with delayed hair cycle phases and growth retardation of adipocytes, suggesting HtrA2's role in regulating adipogenesis-related hair growth.
February 1990 in “PubMed” This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.
317 citations
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August 1997 in “The Plant Journal” This study observed that while calcium influx does not initiate root hairs in Arabidopsis thaliana, it may be crucial for sustaining their elongation through elevated calcium levels at the root hair tip.
81 citations
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January 2003 in “The FASEB Journal” This study found that follistatin and activin interactions are important for hair follicle development and cycling in mice, suggesting that they may regulate processes involving BMP-2 and its antagonist.
71 citations
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June 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that PLGA nanospheres improved scalp-pore permeability and enhanced hair growth activities in mice, suggesting their potential as drug delivery carriers for hair growth ingredients.
53 citations
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October 2012 in “The FASEB Journal” This study found that bimatoprost stimulated hair growth in both human scalp follicle cultures and mouse pelage in vivo, suggesting it might offer a promising treatment for scalp alopecias.
31 citations
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September 2009 in “Natural Product Research” In this study, petroleum ether extract of Citrullus colocynthis fruit effectively promoted hair growth in a mouse model of androgen-induced alopecia, showing comparable results to the standard treatment, finasteride.
30 citations
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February 2017 in “Histochemistry and Cell Biology” This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.
26 citations
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January 2015 in “PubMed” This study found that the type IV collagenases, MMP-2 and MMP-9, play significant roles in the hair cycle, potentially through their influence on VEGF, IGF-1, and TGF-β expression.
24 citations
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December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
12 citations
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March 2021 in “Molecules” This study found that a cedrol nanoemulsion improved hair growth and bioavailability compared to an ointment, demonstrating enhanced efficacy in vitro and in vivo.
9 citations
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July 2021 in “Frontiers in Pharmacology” This study found that intradermal injection of cholesterol-modified siRNA targeting FGF5 or FGF18, or topical application of FGF18-targeted siRNA, effectively influenced hair follicle cycles in mice, suggesting potential benefits for alopecia management.
7 citations
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February 2013 in “Tropical Journal of Pharmaceutical Research” In this study, applying G. glabra root extract to female rats resulted in faster and more extensive hair growth than minoxidil or a control treatment.
5 citations
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November 2015 in “International Journal of Radiation Biology” This study suggests that gamma-ray irradiation affects hair follicle density, structure, and pigmentation in mice, with some changes observed in later hair cycles.
3 citations
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October 2003 in “Annals of Oncology” This case study reported a rare and delayed onset of alopecia in a patient after paclitaxel chemotherapy, potentially influenced by the interaction of thyroid hormones and chemotherapy affecting hair follicle cycles.