Faculty Opinions Recommendation of Mechanical Stretch Induces Hair Regeneration Through the Alternative Activation of Macrophages

    October 2020 in “ Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ”
    Sabine Werner
    Studysummary This study found that applying the right mechanical stretch to skin can activate hair stem cells and promote hair regeneration through a pathway involving WNT, BMP-2, and M2 macrophages.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015
    2. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015
    3. Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia British Journal of Dermatology · 2014
    4. Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss? International Journal of Trichology · 2014
    5. Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth International Journal of Trichology · 2012
    6. Multi-Layered Environmental Regulation on the Homeostasis of Stem Cells: The Saga of Hair Growth and Alopecia Journal of Dermatological Science · 2012
    7. Analyses of Regenerative Wave Patterns in Adult Hair Follicle Populations Reveal Macro-Environmental Regulation of Stem Cell Activity ˜The œInternational journal of developmental biology · 2009