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Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

PGD2 stops hair growth and is higher in bald men with AGA.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Some medicinal plants can help heal wounds and may lead to new treatments.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Testosterone's muscle-building effects do not require its conversion to DHT.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.