Double-Blind Randomized Placebo-Controlled Study of the Efficacy and Safety of Hair Loss Prevention Shampoo Containing Salicylic Acid, Panthenol, and Niacinamide in Alopecia Patients

April 2022 in “ Toxicology and Environmental Health Sciences ”

Hee-Taek Kim, Hye-Su Park, Yongmin Kim, In-Chul Lee, Sang-Jun Lee, Jae‐Suk Choi

salicylic acid panthenol niacinamide alopecia hair loss prevention shampoo Vitamin B5 Vitamin B3

From the encyclopedia

Studysummary This double-blind randomized placebo-controlled study found that a shampoo containing salicylic acid, panthenol, and niacinamide significantly increased hair count and improved hair loss symptoms in alopecia patients over 24 weeks, compared to a placebo, with no abnormal symptoms reported. Our plain-language summary of this paper — not a Tressless recommendation.

In a double-blind randomized placebo-controlled clinical study involving 42 alopecia patients over 24 weeks, a hair loss prevention shampoo containing salicylic acid (0.2%), panthenol (0.2%), and niacinamide (0.1%) was found to be effective and safe. The treatment group showed a significant 17.76% increase in the number of hairs on the crown compared to the placebo group (p < 0.05). Other measures such as visual evaluation of hair loss symptoms, the crown, the line of forelock, and hair thickness also showed significantly greater increases in the treatment group (p < 0.05). No abnormal symptoms were observed, indicating the shampoo's safety. The study concludes that this shampoo can help prevent hair loss in alopecia patients.

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Research cited in this study

11 / 11 results

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