Double-Blind Randomized Placebo-Controlled Study of the Efficacy and Safety of Hair Loss Prevention Shampoo Containing Salicylic Acid, Panthenol, and Niacinamide in Alopecia Patients

    April 2022 in “ Toxicology and Environmental Health Sciences ”
    Hee-Taek Kim, Hye-Su Park, Yongmin Kim … Jae‐Suk Choi
    Studysummary This double-blind randomized placebo-controlled study found that a shampoo containing salicylic acid, panthenol, and niacinamide significantly increased hair count and improved hair loss symptoms in alopecia patients over 24 weeks, compared to a placebo, with no abnormal symptoms reported.
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    Research cited in this study 11

    1. Pharmacological Therapeutics in Androgenetic Alopecia Journal of The Korean Medical Association · 2020
    2. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    3. Topical Niacinamide Does Not Stimulate Hair Growth Based on the Existing Body of Evidence International Journal of Cosmetic Science · 2020
    4. Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial Biological & Pharmaceutical Bulletin · 2015
    5. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    6. A Novel Cosmetic Approach to Treat Thinning Hair British Journal of Dermatology · 2011
    7. Effects of a New Mild Shampoo for Preventing Hair Loss in Asians Using a Simple Hand-Held Phototrichogram Technique International Journal of Cosmetic Science · 2011
    8. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    9. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    10. Topical Use of Minoxidil in Children and Systemic Side Effects Dermatology · 2007
    11. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977

    Related research 2

    1. Shampoo, Conditioner, and Hair Washing International journal of research in dermatology · 2021
    2. The Efficacy and Safety of AP-FHG0604T on Female Pattern Hair Loss: A Randomized Double-Blind Placebo-Controlled Clinical Trial Journal of Clinical Dermatology · 2007