Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial

December 2015 in “ Biological & Pharmaceutical Bulletin ”

Jae-Suk Choi, Jae Yong Park, Woi-Sook Moon, Jin Soo Moon, Sang H. Son, Miryung Kim

Rice Bran Supercritical CO2 Extract RB-SCE androgenic alopecia hair density hair diameter Rice Bran Extract

TLDR Rice Bran Supercritical CO2 Extract significantly increased hair density and diameter in male alopecia patients without any side effects.

In 2015, a 16-week double-blind randomized controlled trial involving 50 alopecia patients was conducted to evaluate the safety and efficacy of Rice Bran Supercritical CO2 Extract (RB-SCE) in treating androgenic alopecia. The study found that RB-SCE significantly increased hair density and diameter in male subjects, with no adverse reactions reported. The treatment was also well-received by patients. However, the study had limitations including a small number of subjects and lack of blood chemistry research. Further studies with larger sample sizes and more comprehensive research methods were recommended.

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18 / 18 results

research Acute Dermal and Ocular Irritation Testing of Rice Bran Supercritical CO2 Extract (RB-SCE) and 0.5% RB-SCE Essence Product

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research 5α-Reductase Type 1 Inhibition of Oryza Sativa Bran Extract Prepared by Supercritical Carbon Dioxide Fluid

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Finasteride effectively treats male pattern baldness, improving hair growth and density.

research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss

219 citations , April 2004 in “Journal of The American Academy of Dermatology”

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research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , September 2002 in “Journal of The American Academy of Dermatology”

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research Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment

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research Evaluation of Sexual Function in Subjects Taking Finasteride for the Treatment of Androgenetic Alopecia

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research The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women

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research The First Clinical Trial of Topical Application of Procyanidin B-2 to Investigate Its Potential as a Hair Growing Agent

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Procyanidin B-2 lotion might help men grow thicker hair without side effects.

research Hair Regrowth

118 citations , April 1998 in “Dermatologic Clinics”

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research Photographic Documentation of Hair Growth in Androgenetic Alopecia

102 citations , October 1996 in “Dermatologic Clinics”

Photographic documentation crucial for evaluating hair growth in androgenetic alopecia.

research Contact Dermatitis in Reaction to 2% Topical Minoxidil Solution

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1 / 1 results

research Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial

7 citations , December 2015 in “Biological & Pharmaceutical Bulletin”

Rice Bran Supercritical CO2 Extract significantly increased hair density and diameter in male alopecia patients without any side effects.