Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial

January 2015 in “ Biological & Pharmaceutical Bulletin ”

Jae-Suk Choi, Jae Yong Park, Woi-Sook Moon, Jin Soo Moon, Sang H. Son, Miryung Kim

Rice Bran Supercritical CO2 Extract RB-SCE androgenic alopecia hair density hair diameter Rice Bran Extract

Studysummary This study found that a 16-week dermal application of rice bran extract significantly increased hair density and diameter in male androgenic alopecia patients without causing adverse reactions. Our plain-language summary of this paper — not a Tressless recommendation.

In 2015, a 16-week double-blind randomized controlled trial involving 50 alopecia patients was conducted to evaluate the safety and efficacy of Rice Bran Supercritical CO2 Extract (RB-SCE) in treating androgenic alopecia. The study found that RB-SCE significantly increased hair density and diameter in male subjects, with no adverse reactions reported. The treatment was also well-received by patients. However, the study had limitations including a small number of subjects and lack of blood chemistry research. Further studies with larger sample sizes and more comprehensive research methods were recommended.

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