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Lower finasteride doses had more side effects; dutasteride caused back pain; more research needed on post-finasteride syndrome.

This study validated an HPLC analytical method for evaluating fenasteride in commercial products, finding it to be sensitive, selective, and within acceptance criteria for specificity, precision, and stability, making it suitable for quality control testing.

This study presents a validated HPTLC method for simultaneously determining five BPH drugs, showing high sensitivity and selectivity for potential use in quality-control analysis.

This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.

This study found significant signals of sexual dysfunction associated with finasteride use, particularly in younger patients treated for alopecia, though confounding factors may partly contribute to reported cases.

This article examines the PCPT study on whether daily finasteride can reduce prostate cancer incidence, describing its methodology and findings but reporting no new clinical results.

This study found that the risk of persistent sexual dysfunction was higher in men who stopped using finasteride 1 mg compared to omeprazole users.

This study observed that higher PFAS concentrations during adolescence were linked to later pubertal development and lower estradiol levels in females, but not in males, potentially due to PFAS excretion with menstrual fluid.

This study found that variations in (CAG)n and (GGN)n polymorphisms in the androgen receptor gene appear to influence symptom severity in men with post-finasteride syndrome.

In this retrospective study, researchers found that coadministration of finasteride and sildenafil in patients with benign prostatic hyperplasia improved both lower urinary tract symptoms and sexual function, without significant changes in vital signs, after a treatment period averaging 18 weeks.

This review discusses frontal fibrosing alopecia, noting its frequent misdiagnosis and highlighting the need for larger studies to better understand its epidemiology, causes, and treatment options; it reports no new clinical findings.

This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.

P-3074 effectively blocks scalp DHT better than oral finasteride.

Finasteride may cause more sexual side effects than previously thought.

Systematic end-of-trial biopsies are the most reliable way to assess outcomes.

This study found that women with polycystic ovary syndrome had significantly higher levels of the protein fetuin-A compared to healthy controls.

This commentary discusses Post-Finasteride Syndrome as a challenge for clinicians and provides no new clinical results; the author focuses on the condition's manageability.

This study examined the effects of finasteride on human Leydig cells and found altered methylation in dopaminergic pathways, suggesting potential epigenetic contributions to post-finasteride syndrome, warranting further investigation.

This study found that psychiatric adverse drug reactions were more frequently reported with finasteride than with dutasteride, but it remains unclear if there is a causal relationship.

This study found that the oral Janus kinase inhibitor CP-690,550 has a direct effect on reducing pruritus in patients with psoriasis, independent of clinician-assessed improvements in psoriasis severity.

Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.

This review from the 2013 Keogh Review found that non-surgical cosmetic interventions in the UK are largely unregulated, leaving patients with little protection or recourse.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

The MHRA announced on 11 May 2026 that it will update the product information for finasteride and dutasteride to include more details on potential psychiatric and sexual side effects, following a review of existing evidence.

This study observed that finasteride therapy reduced PSA levels by about 40% over a year in Chinese patients with benign prostatic hyperplasia, with varying effects based on baseline PSA levels.

This theoretical paper proposes that a subset of Post-Finasteride Syndrome cases may be driven by a gut-derived toxic process involving hydrogen sulphide-producing bacteria, suggesting that the small intestinal microbiome could be a potential target for treating this condition.

In this study, researchers reported significant improvement in sexual function and related symptoms for four patients using off-label flibanserin, suggesting potential broader applications beyond premenopausal women with hypoactive sexual desire disorder.

In this study, a 75% ethanol extract of Fructus Psoraleae was found to significantly inhibit 5-α reductase and promote hair growth in mice, indicating its potential as a treatment for androgenetic alopecia through modulation of the Nrf2-Keap1 pathway.

The researchers reported that both finasteride and PM-9 competitively inhibit the 5 alpha-reductase enzyme in P. crustosum broth.

This review article examines the current understanding of frontal fibrosing alopecia, noting its prevalence in different demographics and the roles of genetic and environmental factors in its pathogenesis, while highlighting that treatment approaches remain varied and lack standardization.