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In this study, reports from individuals using Serenoa repens indicated a possible post-Serenoa syndrome characterized by persistent sexual and neuropsychiatric symptoms, with causality assessed as 'probable' in 54% of cases, highlighting an underrecognized safety concern that warrants further investigation.

Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.

In this study, PFOS exposure altered steroid hormone levels and enzyme activities related to steroidogenesis in juvenile Silurana tropicalis, with effects differing between male and female frogs.

This abstract provides a brief introduction to Propecia® (finasteride 1mg) but reports no new research findings.

This study found an IFIS incidence rate of 3.18% among cataract surgeries in a Chinese hospital and identified reserpine, clozapine, and post-panretinal photocoagulation as new risk factors.

This study used high-resolution ultrasound to investigate the pathophysiology of persistent erectile dysfunction in young men who used the drug finasteride, observing differences in erectile tissue homogeneity compared to control subjects without finasteride exposure.

This study found that Puerariae Flos extract inhibited testosterone 5α-reductase and promoted hair growth in mouse models, suggesting its potential use for treating androgenic alopecia.

This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.

This study found that utilizing a clinical pharmacist in perioperative urological services reduced surgical cancellations and resident overtime while improving service efficiency and financial sustainability.

This article reviews ongoing concerns about the safety of 5α-reductase inhibitors like finasteride, highlighting the lack of long-term data on persistent depression and sexual side effects after drug discontinuation; no new clinical results are reported.

Finasteride for female hair loss has low side effects, more research needed.

This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.

This study found that reports of suicidal ideations linked to oral finasteride were significantly higher in 2013–2018 and 2019–2023 compared to 2006–2011, potentially due to increased awareness of post-finasteride syndrome from 2012 onward. No such signals were seen with oral dutasteride.

This study explores the controversial condition known as post‐finasteride syndrome, observed in some men who experience lasting sexual, neurological, and psychological side effects after stopping finasteride, emphasizing its rarity and the lack of proven treatments.

This study reports that finasteride does not save lives despite initial concerns about its risks, and its potential role in reducing PSA test overdiagnosis is questioned due to other associated harms.

This study found that lipid accumulation product (LAP) and free androgen index (FAI) can highly predict liver steatosis in women with PCOS phenotype A.

The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.

This study found that a novel saw palmetto supercritical CO2 extract effectively inhibits 5α-reductase type II in vitro, suggesting its potential for promoting prostate health in benign prostatic hyperplasia.

This review concluded that WS PRO 160 I 120 mg, a herbal preparation, may be an effective and safer alternative to standard drugs for treating lower urinary tract symptoms in men with benign prostatic hyperplasia.

This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.

Psoriasis patients experience moderate functional impairment related to disease severity and less satisfaction.

This meta-analysis reported that the use of 5α-reductase inhibitors significantly increased the risk of postfinasteride syndrome-like adverse effects in men treated for benign prostatic hyperplasia or androgenetic alopecia.

This study found that poly(propylene carbonate maleate) microspheres can successfully prolong finasteride release over 42 days, showing potential for long-term sustained drug delivery.

A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.

Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.

Finasteride effectively reduces symptoms of male chronic pelvic pain syndrome with few side effects.