A Study of Risk Factors and Predictive Factors in Intraoperative Floppy Iris Syndrome During Phacoemulsification

    Jiexin Yu, Ke Yao
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    Studysummary This study found an IFIS incidence rate of 3.18% among cataract surgeries in a Chinese hospital and identified reserpine, clozapine, and post-panretinal photocoagulation as new risk factors.
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    The study aimed to determine the incidence and risk factors of intraoperative floppy iris syndrome (IFIS) during phacoemulsification in a Chinese hospital. Among 807 patients (1,068 eyes), IFIS was observed in 34 eyes, indicating an incidence rate of 3.18%. The study found strong positive correlations between IFIS and the use of medications such as finasteride, tamsulosin, reserpine, and clozapine, as well as post-panretinal photocoagulation. A dilated pupil size smaller than 7.25 mm was predictive of IFIS, with pupil size inversely related to its incidence. Reserpine, clozapine, and post-panretinal photocoagulation were identified as new risk factors for IFIS.
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