Risk Factors for Intraoperative Floppy Iris Syndrome: One Year Prospective Study

August 2013 in “ Acta Ophthalmologica ”

Irini Chatziralli, Efstratios Parikakis, Vasileios Peponis, Aggeliki Maniatea, Panagiotis Mitropoulos

TLDR Certain medications, hypertension, and short eye length increase the risk of Intraoperative Floppy Iris Syndrome during cataract surgery.

This study aimed to evaluate risk factors for Intraoperative Floppy Iris Syndrome (IFIS) in patients undergoing phacoemulsification cataract surgery. The study involved 1,024 patients, and IFIS was observed in 61 cases (5.9%). The research confirmed that the use of alpha1-adrenergic receptor antagonists such as tamsulosin, alfuzosin, and terazosin was associated with IFIS. Additionally, benzodiazepines, quetiapine, hypertension, and short axial length were identified as potential risk factors. Interestingly, the duration of alpha-blocker intake did not correlate with IFIS occurrence.

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