Frontal Fibrosing Alopecia

    July 2018
    Barbara Obradović
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    Studysummary This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.
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    Frontal fibrosing alopecia (FFA) was a scarring alopecia primarily affecting postmenopausal women, with a mean onset age of 56 years. It involved progressive frontotemporal hairline recession and eyebrow loss, with severe cases showing eyelash or body hair involvement and non-inflammatory facial papules. The pathogenesis was unclear but likely involved autoimmune and hormonal factors. Diagnosis relied on clinical patterns and trichoscopy. No established therapy existed, but 5-alpha-reductase inhibitors like finasteride and topical immunomodulators like pimecrolimus showed effectiveness. Early diagnosis and treatment were crucial to prevent permanent hair loss and psychological effects.
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