Search
for

    GlossaryTopical Calcineurin Inhibitors (topical immunomodulators)

    medications applied to skin to reduce immune responses

    Topical Calcineurin Inhibitors (TCIs) are medications applied to the skin to reduce inflammation and immune responses. They work by blocking the activity of calcineurin, a protein that activates T-cells in the immune system, making them useful in treating conditions like eczema and vitiligo. Unlike corticosteroids, TCIs do not cause skin thinning, making them a safer long-term option for sensitive areas.

    Related Terms

    Learn

    5 / 22 results

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

    Research

    5 / 1000+ results

    Community Join

    5 / 1000+ results

      community Fin/dut ONLY users, this has been my experience so far

      in Finasteride/Dutasteride  97 upvotes 3 months ago
      The user has been using finasteride for hair loss since January 2023, initially seeing improvement but now experiencing increased thinning. They are considering other factors like thyroid and insulin resistance and are seeking advice from long-term finasteride users, while some suggest trying dutasteride, minoxidil, or consulting a dermatologist for further evaluation.

      community Is Topical Finasteride Safe for Cats in My Home?

      in Finasteride  46 upvotes 1 week ago
      Topical finasteride is not known to be toxic to cats like minoxidil, but careful handling is advised to prevent ingestion or skin contact. OP seeks reassurance to convince their girlfriend of its safety around their cat.

      community Topical minoxidil + Oral Finasteride 5 months

      in Progress Pictures  81 upvotes 1 week ago
      The user experienced significant hair regrowth using topical Minoxidil and oral Finasteride over five months, with darker and thicker hair and new follicles appearing. They are considering waiting 1-2 years before deciding on a hair transplant, as further improvement is expected.

      community Topical Finasteride Users – When Did Your Shedding Stabilize? (DUPA Case)

      in Treatments  112 upvotes 1 week ago
      The user is using a self-made topical mix of finasteride and minoxidil foam for hair loss, experiencing solid regrowth in the frontal area and mild improvement at the crown, but still shedding. They previously used oral finasteride and dutasteride but stopped due to side effects, and are seeking advice on when shedding might stabilize with the topical treatment.