Pharmacovigilance Analysis of Reports of Sexual Dysfunction Associated with Finasteride Use: Implications for the Post-Finasteride Syndrome

    April 2022 in “ The Journal of Sexual Medicine ”
    Duong Nguyen, P. Herzog, Eugene B. Cone, M. Labban, K. Zorn, Bilal Chughtai, Shehzad Basaria, Dean Elterman, Q-D. Trinh, Naeem Bhojani
    TLDR Finasteride is linked to sexual dysfunction, especially in younger users treating hair loss.
    This study analyzed 7,700 reports of sexual dysfunction associated with finasteride, a drug used for androgenetic alopecia and benign prostatic hyperplasia, using the WHO's VigiBase. The findings revealed a significant disproportionality signal for sexual dysfunction, particularly in patients under 45 and those using finasteride for alopecia, with a reporting odds ratio (ROR) of 64.9 for alopecia patients. Sensitivity analyses confirmed the significance of these signals, suggesting that while some reports may be influenced by indication and reporting biases, these factors alone do not fully explain the observed effects in younger alopecia patients.
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      community 1 month of using fin, so happy

      in Progress Pictures  869 upvotes 9 months ago
      User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

      community Another clueless guy fearmongering and spreading misinformation

      in Chat  251 upvotes 1 year ago
      The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

      community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

      in Research/Science  11 upvotes 5 months ago
      Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 2 years ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

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