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This study found that PRX102, a peroxidase with a unique polar localization pattern, plays a role in root hair growth by aiding the transport of materials to the tips of growing root hairs.

This study concluded that finasteride is a viable first-line treatment for moderate uncomplicated benign prostatic hyperplasia, particularly in patients with larger prostates, by significantly reducing acute urinary retention and the need for surgery.

This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.

This study found that exposing dermal papilla cells to sub-lethal doses of colchicine releases histone H4, which inhibits cell growth and decreases alkaline phosphatase activity, potentially explaining colchicine-induced hair loss.

This study constructed a model to predict finasteride's inhibitory activity on 5α-reductase type 2 and calculated that a 1 μM plasma concentration, after 50 mg administration, matches prostate inhibition levels.

This study observed that radioactive sulphur appeared in rat and mouse hair follicles more quickly than in lambs, possibly linked to faster hair growth rates in the rodents.

This study demonstrated that PGF 2α significantly stimulates hair growth in human hair follicles via a receptor-driven mechanism, with a notably stronger response in intermediate follicles than in terminal ones, suggesting potential clinical significance for conditions like alopecia.

This study examined the demographics of patients diagnosed with pernio and compared their vitamin B12, folate, and ferritin levels with those of a control group.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

This study demonstrated that 12 months of 5 mg daily finasteride treatment reduced prostate volume, dihydrotestosterone, and prostate-specific antigen levels, while improving urinary flow rates and symptom scores in benign prostatic hyperplasia patients.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

PRP preparation partially activates platelets, causing varied growth factor release.

This study found that expressing certain PIN proteins in Arabidopsis root hairs inhibited growth by decreasing auxin levels, while PIN5 slightly stimulated growth, demonstrating differential effects on auxin transport.

This study found that PPAR alpha, -delta, and -gamma are expressed in human hair follicle cells, and clofibrate exhibited a beneficial effect on hair follicle survival in culture within a specific concentration range.

This study explored the localization of phenolsulphotransferase in human embryonic and fetal kidneys, finding distinct patterns of PST immunoreactivity in developing mesonephric and metanephric structures over time.

This study developed a fully automated HPLC method for accurately quantifying finasteride in human plasma, achieving a detection limit of 1 ng/ml with validated application in pharmacokinetic studies.

This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.

This study found that finasteride significantly inhibits the metabolism of tirilazad to its active metabolites without greatly affecting tirilazad's overall clearance.

This study found that KF19418 stimulated hair follicle growth in vitro and accelerated hair regrowth in a mouse alopecia model, with effects comparable to minoxidil.

Bath PUVA therapy works well for a skin condition without as many cancer risks and is cheaper, and iron deficiency might not cause female hair loss.

This study established a method using reversed-phase high performance liquid chromatography to determine finasteride concentration in hair cosmetics, showing a strong linear relationship with mass concentration and recoveries between 90.3% and 102.0%.

This study found that formalin-induced pain in rats nearly eliminates testosterone in the brain and spinal cord by likely increasing 5α-reductase activity, but normalizes serum levels after 24 hours.

This study developed and validated an HPLC method to quantify impurities in finasteride, demonstrating its suitability for quality assurance of the drug and its related substances.

This study observed that repeated hair follicle sampling is feasible and reliable for measuring FMR1 mRNA and FMRP in individuals with Fragile X syndrome, supporting its use in longitudinal studies.

This article updates a prior work on pharmacophore modeling and highlights the advances in 3D database searching technologies for drug design, without presenting new research findings.

This study developed a new crystallization method using solid solution formation to purify finasteride by effectively removing contamination with dihydrofinasteride.

This study developed a precise and simple HPLC method for estimating tamsulosin and finasteride simultaneously in pharmaceutical forms, demonstrating good precision and potential usefulness for combined dosage analysis.

This study found that pneumatic skin flattening (PSF) significantly reduces pain and post-treatment erythema during high-energy IPL and laser hair removal while enhancing treatment efficacy.