Determination of Finasteride in Anti-Calvous Hair Cosmetics by High Performance Liquid Chromatography
January 2014
in “
China Surfactant Detergent & Cosmetics
”
New to Finasteride? There is a guide in the encyclopedia. Read the guide → Studysummary This study established a method using reversed-phase high performance liquid chromatography to determine finasteride concentration in hair cosmetics, showing a strong linear relationship with mass concentration and recoveries between 90.3% and 102.0%. Our plain-language summary of this paper — not a Tressless recommendation.
The study established a method using reversed-phase high performance liquid chromatography to determine finasteride levels in anti-calvous hair cosmetics. The analysis was conducted on an Agilent Zorbax Extend C18 column with a detection wavelength of 220 nm at 30°C, using a mobile phase of acetonitrile and KH2PO4 with a gradient model at a flow rate of 1.0 mL/min. The results indicated a strong linear relationship (R² = 0.9990) between finasteride mass concentration (0.8-20 mg/L) and peak area. The recovery rates for finasteride ranged from 90.3% to 102.0%.
