This case series observed that patients with persistent post-COVID-19 symptoms reported considerable improvement after using icosapent ethyl, suggesting potential therapeutic success warranting further research.
This hypothesis paper suggests that sexual and cognitive dysfunctions reported by some men after using finasteride and dutasteride may stem from vascular and tissue changes in penile tissue triggering broader inflammatory effects.
13 citations
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February 2006 in “Clinical and Experimental Dermatology” A benign tumor developed at a girl's BCG vaccination site, not previously linked to the vaccine.
3 citations
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January 2012 in “Journal of cosmetics, dermatological sciences and applications” This descriptive study reported that cutaneous issues, particularly anesthesia and neuropathy dermatitis, were common at saphenous vein harvesting sites in Iraqi patients who underwent coronary artery bypass surgery.
353 citations
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February 2022 in “Nature Immunology” This review explores post-COVID-19 syndromes and the underlying mechanisms, including persistent inflammation, autoimmunity, and possible viral reservoirs, but reports no new clinical results.
4 citations
,
December 2021 in “Experimental and Therapeutic Medicine” This article describes adult female acne as a complex condition affected by genetic, hormonal, and environmental factors, with hormonal therapies highlighted as particularly valuable for treatment.
1 citations
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April 2022 in “Global health & medicine” This review explores long COVID symptoms in Japan and discusses potential contributing factors, highlighting persistent SARS-CoV-2 infection's role, but reports no new clinical results; it also considers vaccination as a treatment option.
2 citations
,
June 2023 in “PeerJ” This review discusses how chronic inflammation can lead to persistent stem cell activation and DNA damage, ultimately promoting cancer development and metastasis, but reports no new results.
This review concludes that chronic inflammation persistently activates stem cells, leading to DNA damage accumulation that can promote cancer development and metastasis, affecting both stem and cancer cells.
March 2026 in “South Asian Research Journal of Medical Sciences” In this case study, a 7-year-old boy with kerion celsi experienced persistent inflammation even after microbiological clearance; dermoscopic-guided removal of hair and keratin debris improved his condition, suggesting a novel inflammatory mechanism involving granulomatous response to keratinous debris in tinea capitis.
This review concluded that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage and promoting cancer development and metastasis from stem cell origins.
This review concludes that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage that promotes cancer development and metastasis, by affecting normal stem cells, cancer stem cells, and cancer cells.
This literature review reports that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage, and eventually promoting cancer development and metastasis even before stem cells become cancerous.
This review concludes that chronic inflammation can lead to persistent activation of stem cells, which may accumulate DNA damage and ultimately promote cancer, while also facilitating cancer metastasis.
April 2023 in “Dermatology practical & conceptual” This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.
1 citations
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June 2007 in “Journal of Clinical Oncology” This study found that weekly low-dose bicalutamide was safe and appeared to be associated with high-grade PIN remission and favorable PSA modulation in subjects with persistently elevated PSA but negative biopsy.
4 citations
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October 2025 in “Journal of Cosmetic Dermatology” This study reported severe and persistent skin reactions, including inflammation and scarring, after intradermal injections of unregulated exosome-based products, highlighting potential risks in aesthetic dermatology.
38 citations
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November 2006 in “Pediatric dermatology” This study reports four infants with necrotic caput succedaneum leading to alopecia and persistent scalp lesions, which partially improved with topical corticosteroids, indicating erosive pustular dermatosis of the scalp.
2 citations
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October 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Aire‒/‒ mice spontaneously developed persistent AA-like lesions, highlighting a potential role for AIRE in hair follicle biology and pathogenesis of alopecia areata.
8 citations
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March 2001 in “PubMed” This case study reports a 38-year-old epileptic man with tufted hair folliculitis that persisted despite various antibiotic treatments, showing transient improvement followed by recurrence.
14 citations
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August 2022 in “Lupus Science & Medicine” This study found two patterns of Type 2 SLE symptoms: Intermittent symptoms resolving with Type 1 symptom remission and Persistent symptoms continuing regardless of Type 1 symptom activity.
10 citations
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September 2022 in “Psychiatry and Clinical Neurosciences” This review discusses post-acute sequelae of SARS-CoV-2 infection, highlighting the challenges in diagnosing and managing the variety of persistent symptoms, and reports no new clinical results.
8 citations
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April 2024 in “The Journal of Dermatology” This study suggests that neuropeptides may contribute to the progression of alopecia areata by causing neurogenic inflammation and disrupting the inflammatory environment of hair follicles, but the exact pathogenesis still requires further investigation.
16 citations
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December 2015 in “Journal of Investigative Dermatology” This study found significant gene expression abnormalities in hair follicles affected by alopecia areata, suggesting persistent changes that may predispose to future relapses even after hair regrowth.
13 citations
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March 2000 in “Veterinary Dermatology” This study characterized a novel form of mural folliculitis in dogs, resembling human pseudopelade, marked by persistent alopecia, lymphocyte infiltration, and severe follicular atrophy without effective treatment response.
November 2021 in “Transplantation direct” This case report highlights that Demodex folliculitis in an immunocompromised patient can result in severe and widespread eruptions, which were effectively treated with oral ivermectin and topical permethrin.
127 citations
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January 2000 in “Journal of Investigative Dermatology” This study found that pro-inflammatory cytokines and apoptotic mechanisms, specifically involving granzyme B and Fas pathways, are associated with chronic alopecia areata, indicating their potential role in the disease's persistence.
January 2025 in “Pakistan Veterinary Journal” This study examined the effects of microneedling on dogs with non-inflammatory alopecia and found that it may aid hair regrowth, especially for those with controlled endocrine disorders but persistent alopecia, as demonstrated by hair regrowth observed over 12 months in specific cases.
January 2008 in “International Journal of Trichology” This paper examines three case studies of hair disorders through the lens of analytical psychology, suggesting that psychological factors and symbolic meanings may contribute to their onset and persistence.
April 2024 in “Military Medical Research/Military medical research” This review explores the current and experimental therapies for chronic wounds, emphasizing the potential of cellular and immunotherapies in addressing these persistent conditions, but notes a shortage of comprehensive studies on their effectiveness.