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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The meeting highlighted major advances in skin research, including new findings on skin microbes, genetic links to skin diseases, and improved treatments for various conditions.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

PRP treatment for hair loss shows promise, with 58% of patients satisfied and most noticing improvement within 6 months.

The moisturizer with phytol improved skin texture and reduced fine wrinkles better than the moisturizer without it.

A woman with a skin disorder was found to have hepatitis C, which may be linked, and was safely treated with methotrexate.

PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.

Plant-based ingredients are effective and safe for modern skincare products.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

The document concludes that diagnosing female hair loss requires careful examination, with treatments varying by condition and psychological support often necessary.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

Korean Red Ginseng saponins may protect skin from inflammation and darkening caused by air pollution.

AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.