Saponins of Korean Red Ginseng May Protect Human Skin from Adipokine-Associated Inflammation and Pigmentation Resulting from Particulate Matter Exposure

    February 2022 in “ Nutrients ”
    Ik Jun Moon, WooHyeong Kim, Su Yeon Kim … Sung Eun Chang
    Studysummary In this study, saponins from Korean red ginseng were found to protect against the harmful effects of airborne particulate matter on human skin cells by reducing oxidative stress, inflammation, leptin expression, and melanin production.
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    Research cited in this study 5

    1. HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro Molecular Medicine Reports · 2021
    2. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018
    3. Particulate Matter 2.5 Damages Skin Cells by Inducing Oxidative Stress, Subcellular Organelle Dysfunction, and Apoptosis Archives of Toxicology · 2018
    4. Antimelanogenic Effect of Ginsenoside Rg3 Through Extracellular Signal-Regulated Kinase-Mediated Inhibition of Microphthalmia-Associated Transcription Factor Journal of Ginseng Research · 2015
    5. Red Ginseng Extract Promotes Hair Growth in Cultured Human Hair Follicles Journal of Medicinal Food · 2014