57 citations
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July 2000 in “Toxicology Letters” This study found that the K6/ODC transgenic mouse model is highly sensitive to identifying genotoxic carcinogens, showing 100% concordance with traditional rodent bioassays.
This study found that bitter melon leaf extract, particularly at a 10% concentration, promoted hair growth in male rabbits, outperforming the effect of a 2% minoxidil solution.
September 2022 in “Journal of Sulaimani Medical College” In this study, the combination of topical minoxidil 5% and betamethasone valerate 0.1% achieved slightly higher depigmentation in vitiligo of hair-bearing areas but did not show significant improvement over betamethasone valerate alone.
October 2023 in “Journal of Pakistan Association of Dermatologists” In this study, reflectance confocal microscopy was shown to provide early insights into sub-clinical treatment progress in patients with androgenetic alopecia, potentially offering advantages over global photography.
10 citations
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July 2013 in “British Journal of Dermatology” High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.
June 2021 in “International Journal of Ayurveda and Pharma Research” This conceptual paper proposes evaluating the Ayurvedic formulation Moorvadi choornam for alleviating side effects of chemotherapy, including symptoms consistent with Garavisha lakshanas, but reports no clinical outcomes.
1 citations
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August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study developed a new method to analyze Cantú syndrome mutations in KATP channels, finding that while Kir6.1 mutations increase sensitivity to potassium channel openers, SUR2B mutations show reduced sensitivity, but both result in marked hyperpolarization compared to wild-type channels under basal conditions.
May 2006 in “Frontiers in Neuroendocrinology” This study found that patients with androgenic alopecia had altered neuroactive steroid levels and depression symptoms after stopping finasteride treatment, suggesting lingering neuropsychiatric effects.
69 citations
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January 2002 in “Journal of biomedical optics” This study found that commercially available dyes penetrate up to 1.2 mm into human skin, with Indocyanine Green binding to cell proteins and showing a shift in absorption peak.
This study found that depressed individuals had higher levels of sodium and potassium in their hair and lower antidiuretic hormone levels, similar to changes observed in weightless conditions experienced by astronauts.
1 citations
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September 1986 in “Journal of the Forensic Science Society” This study found that hair root sheaths can be accurately typed for erythrocyte acid phosphatase, adenylate kinase, and adenosine deaminase, consistent with blood typing results from the same donors.
2 citations
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October 2018 in “Journal of Mind and Medical Sciences” In this study, researchers developed and validated a method to quantify pyrrolizidine alkaloids in honey and flour, increasing alkaloid recovery rates through successive extractions, achieving up to 86% recovery for honey and 76% for flour.
This study reports on a new semantic annotation approach used to identify substances in MEDLINE abstracts responsible for adverse drug reactions, with promising performance shown by a prototype system.
June 2010 in “Journal of Veterinary Clinics” This study established an experimental model to visualize calcium ion distribution after skin barrier damage in canine epidermis, observing that calcium gradients changed differently depending on the type of damage and time elapsed.
16 citations
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May 1995 in “Biochemical and Biophysical Research Communications” In this study, researchers found that both thermolabile and thermostable forms of phenol sulfotransferase contribute to the sulfation of minoxidil, emphasizing the need to consider both enzymes in assessing sulfation in human tissues.
May 2010 in “Europe PMC (PubMed Central)” This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.
2 citations
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April 2020 in “Clinical and experimental obstetrics & gynecology” This study measured estradiol and progesterone in the scalp hair of pre- and postmenopausal women using immunoassay, but found no statistical significance in hormone concentration differences between the groups.
December 1990 in “PubMed” This study found that topical application of 17 alpha-propylmesterolone significantly increased proliferative activity in hair matrix cells in men with androgenetic alopecia.
21 citations
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December 2011 in “Chungara” This study shows that environmental contamination affects mummy hair, suggesting that using it to assess ancient people's health or nutrition should be approached cautiously.
January 2016 in “Journal of animal research” This study found significant correlations for copper and zinc levels between hair and plasma in Pomeranian and Labrador dogs, but no significant correlation for iron.
January 2004 in “Trace Elements Science” This study observed that hair levels of chromium, manganese, and copper were lower in diabetics compared to controls, while iron levels were higher.
October 2018 in “Exercise Biochemistry Review” In this mouse study, aerobic exercise was found to protect the intestinal mucosal barrier in obstructive jaundice by inhibiting the HMGB1 / TLR4 / NF-κB signaling pathway through the H2S / CSE system.
43 citations
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January 1977 in “Toxicology and Applied Pharmacology” In this study, minoxidil was found to have low toxicity in various animals, with specific heart lesions observed only in dogs at certain doses.
3 citations
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May 2022 in “Journal of The American Academy of Dermatology” This source notes that while low-dose oral minoxidil is effective for treating androgenetic alopecia, it has been associated with electrocardiogram changes and palpitations even at low doses.
62 citations
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December 1941 in “Experimental biology and medicine” In this study, phenylthiocarbamide intake was associated with hair graying in rats, while switching to tap water led some rats to regain their original fur color, suggesting dietary factors influence pigmentation.
August 1946 in “Journal of the American Medical Association” This document discusses website navigation and access options for JAMA without presenting any new research findings.
January 2010 in “Guoji yaoxue yanjiu zazhi” This review discusses thallium poisoning, its mechanisms, clinical symptoms, and treatment approaches, highlighting hemoperfusion as an effective method to eliminate absorbed thallium, though no new clinical results are presented.
6 citations
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May 2014 in “Biomarkers and Genomic Medicine” This review discusses Charnoly bodies as biomarkers of cell injury and potential therapeutic targets in neurodegenerative, cardiovascular, and cancer treatments but reports no new clinical results.
1 citations
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January 2022 in “European Journal of Pharmacology” In this study, FMN was found to inhibit androgen receptor function and androgen-regulated gene expression in prostate cancer cells, suggesting potential as an antiandrogen therapy.
4 citations
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October 2018 in “Journal of Mind and Medical Sciences” This article reviews challenges in managing malignant ureteral obstruction and emphasizes prompt treatment to preserve renal function, but reports no clinical results.