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Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Improving skin barrier and using antifungal treatments can help manage dandruff.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Best hair growth results from combining finasteride and minoxidil.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Advanced human skin models improve drug development and could replace animal testing.

Traditional Chinese medicines with heavy metals can cause severe poisoning.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

LCN may improve finasteride delivery for hair loss treatment.