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Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.

lncRNAs may regulate hair follicle development in Hu sheep.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Alternative treatments show promise for hair growth beyond traditional methods.

Natural products show promise for new hair loss treatments.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Microneedle-assisted therapy with human basic fibroblast growth factor significantly regrew hair in patients with hair loss.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Androgens can help prevent memory problems caused by apoE4.

Lactobacillus plantarum hydrolysates may help increase hair growth by boosting VEGF production.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Follicular Unit Transplantation is a precise hair restoration technique that requires careful planning and a skilled team, and Follicular Unit Extraction offers a less invasive option.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

New treatments for alopecia areata show promise, but more research is needed to confirm their effectiveness.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

AGA risk factors include age, smoking, hypertension for men, and age, dyslipidemia for women; lifestyle changes may help prevention.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Sonic hedgehog proteins may help grow hair.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.