Polycystic Ovary Syndrome and Cardiovascular Disease

February 2012 in “ InTech eBooks ”

Bar nder, Derun Taner, Hamiyet Ylmaz, Mohammed Muzaffer

polycystic ovary syndrome PCOS hyperandrogenism chronic anovulation endocrinopathy

Studysummary This review discusses the impact of polycystic ovary syndrome on cardiovascular risk and reports no new clinical findings.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Polycystic ovary syndrome (PCOS) was identified as the most common female endocrinopathy, affecting up to 10% of women of reproductive age, and was associated with increased cardiovascular risk. The syndrome, characterized by chronic anovulation and hyperandrogenism, was linked to potential long-term consequences, including cardiovascular disease and type 2 diabetes. This connection highlighted the importance of examining PCOS beyond its gynecological implications to understand its broader impact on women's health, particularly in relation to cardiovascular disease risk post-menopause.

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Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.

research Developmental Origin of Polycystic Ovary Syndrome: A Hypothesis

430 citations , July 2002 in “Journal of Endocrinology”

This hypothesis paper suggests that PCOS may result from genetically determined ovarian hypersecretion of androgens, influencing hormone regulation and insulin resistance, with obesity further affecting its severity; no new clinical results are reported.

research Baldness And Coronary Artery Disease: The Dermatologic Point Of View Of A Controversial Issue

50 citations , July 2001 in “PubMed”

This study suggests a potential link between early-onset baldness before age 30 and increased risk for coronary artery disease, warranting consideration in epidemiological research.

research Relationship of the Metabolic Syndrome and Obesity to Polycystic Ovary Syndrome: A Controlled, Population-Based Study

61 citations , February 2001 in “American Journal of Obstetrics and Gynecology”

This study suggests that polycystic ovary syndrome symptoms are uncommon among women with metabolic syndrome, indicating it may represent only a specific subset within the broader context of metabolic syndrome.

research A Prospective Study of the Prevalence of Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain

491 citations , July 2000 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that the prevalence of polycystic ovary syndrome was 6.5% in a minimally biased sample of Caucasian women from Spain.

research Prevalence of Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study

633 citations , September 1998 in “The Journal of Clinical Endocrinology and Metabolism”

This study observed that among a cohort of reproductive-aged women in the U.S., the prevalence of PCOS was about 4.0%, with no significant racial differences between White and Black women.

research Polycystic Ovary Syndrome: Clinical and Biochemical Features

1947 citations , September 1995 in “New England journal of medicine/The New England journal of medicine”

This article discusses the heterogeneity of polycystic ovary syndrome, its association with insulin resistance, and its implications for long-term health, but reports no new clinical results.

research Clinical and Biochemical Parameters of Androgen Action in Normal Healthy Caucasian Versus Chinese Subjects

177 citations , June 1991 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that caucasian subjects had higher serum levels of 5 alpha-reduced androgen metabolites compared to Chinese subjects, suggesting racial differences in 5 alpha-reductase activity and a potential mechanism for increased body hair in caucasian men.