1 citations
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August 2025 in “Journal of Neonatal Surgery” This study evaluated a new nanogel formulation containing Ciclopirox Olamine for treating cutaneous candidiasis, finding that the optimized version offered improved skin penetration, sustained drug release, and effective antifungal action against Candida albicans compared to conventional treatment.
51 citations
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May 2008 in “Mycoses” This study found that terbinafine HCl nail solutions with or without DDAIP HCl significantly outperformed ciclopirox nail lacquer in treating guinea pig dermatophytosis, suggesting potential effectiveness for human nail infections.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and evaluated a polyherbal hair dye using Phyllanthus reticulatus fruit, finding it to be a safe, effective, and environmentally friendly alternative to synthetic dyes, with added antioxidant and antimicrobial benefits for scalp health.
This study found that combining prodigiosin and essential oil from Thuja orientalis leaves showed a synergistic effect against the 3rd larva stage of Cx. pipiens, significantly reducing acetylcholine esterase activity and altering midgut pH, compared to untreated larvae.
October 2017 in “Our Dermatology Online” This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.
7 citations
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March 2013 in “Tetrahedron Letters” This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.
1 citations
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January 2014 This study found that Crataegus pinnatifida extract promoted hair growth in mice by inducing the anagen phase, potentially through activating signaling pathways that enhance cell survival.
1 citations
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May 2022 in “Frontiers in Pharmacology” This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.
33 citations
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October 2013 in “Journal of The American Academy of Dermatology” In this study, pioglitazone treatment in patients with lichen planopilaris showed limited success, with significant improvement seen in only a minority of cases.
May 2024 in “EAS Journal of Pharmacy and Pharmacology” In this study, researchers used molecular docking to show that compounds from pomegranate peels, such as apigenin, luteolin, and taxifolin, effectively inhibit the enzyme 5α-reductase, suggesting potential anti-alopecic properties.
May 2024 in “Reactions weekly”
4 citations
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September 2018 in “Rendiconti lincei. Scienze fisiche e naturali” This study concluded that spikenard specimens in Renaissance Italian herbaria are attributed to Nardostachys jatamansi, a plant used in traditional medicine and cosmetics.
July 2026 in “International Journal of Drug Delivery Technology” This study found that a combination of curcumin and piperine demonstrated moderate antioxidant activity, negligible cytotoxicity, and significant potential for promoting hair regrowth in rat models of alopecia, suggesting it could be a safe and effective natural alternative for managing hair loss.
6 citations
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February 2020 in “Journal of Natural Products” In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.
3 citations
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October 2024 in “Frontiers in Pharmacology” This laboratory study found that PI extract, along with its metabolites Ang and Mac, inhibited cell proliferation and protein expression linked to pathways involved in BPH, suggesting potential for therapeutic use, although the Ang-Mac combination showed no significant effect on apoptosis through the p53 pathway.
26 citations
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February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
2 citations
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March 2021 in “Journal of nanoscience and nanotechnology” This study suggests that nanoliposomes encapsulating saw palmetto CO2 extract could be effective for delivering drugs to treat hair loss due to their small size, dispersion, and negative charge.
7 citations
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January 2017 in “Biological & Pharmaceutical Bulletin” This study found that polyacetylene compounds in Panax ginseng extracts may inhibit neurotrophin receptor binding, suggesting potential therapeutic benefits for alopecia and other hair growth disorders.
February 2025 in “Ciencia Latina Revista Científica Multidisciplinar” This in-silico study found that Finasteride interferes with neurotransmitters and may increase psychopathology when it decomposes into a carboxylic acid similar to Cortisol.
8 citations
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October 2020 in “International Journal of Molecular Sciences” This laboratory study found that nonanal, a plant scent compound, may stimulate growth factors and cell proliferation in human hair follicle dermal papilla cells, suggesting a cAMP-mediated mechanism.
August 2025 in “Anais Brasileiros de Dermatologia” This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.
4 citations
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April 2018 in “Journal of Investigative Dermatology” This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.
76 citations
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February 2015 in “Industrial Crops and Products” This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.
This study found that glycerol most significantly influenced the spreadability and initial viscosity of a saw palmetto anti-hair loss cream, while PEG 400 predominantly affected viscosity changes over time.
7 citations
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August 2007 in “Journal of Biotechnology” 8 citations
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August 2018 in “BMJ Case Reports” This case report describes a patient who experienced rapid hair depigmentation after starting pazopanib for metastatic renal cell carcinoma, which may suggest therapy success despite being distressing.
3 citations
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March 2014 in “Journal of Industrial Microbiology & Biotechnology” This study identified a cytochrome P450 enzyme, CYP-pa1 from Pseudonocardia autotrophica, as responsible for the specific hydroxylation of cyclosporin A at the 9th N-methyl leucine, suggesting potential for biotechnological applications.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that Derinat treatment in mice maintained the hair cycle in the anagen phase and reduced TRPCs-mediated intracellular ROS accumulation, potentially improving hair growth by altering the skin microenvironment.
January 2026 in “Journal of Ethnopharmacology” This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.
9 citations
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December 2021 in “Molecules” This study found that certain metabolites from the plants Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana may support hair follicle growth by promoting dermal papilla cell proliferation, supporting their traditional use in hair care.